Literature DB >> 26186288

Blocking Cancer Growth with Less POMP or Proteasomes.

Alfred L Goldberg1, Jinghui Zhao2, Galen A Collins2.   

Abstract

Although proteasomes are critical in cell regulation and cancer therapy, little is known about the factors regulating proteasome content or activity. In this issue, Zhang et al. (2015) report that miR-101 suppresses the expression of chaperone POMP and 20S assembly, and certain cancers raise proteasome content by losing miR-101.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26186288      PMCID： PMC4787267          DOI： 10.1016/j.molcel.2015.07.005

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  9 in total

1.  The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins.

Authors:  Rosanna Piccirillo; Alfred L Goldberg
Journal:  EMBO J       Date:  2012-07-06       Impact factor: 11.598

2.  IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response.

Authors:  Sylvia Heink; Daniela Ludwig; Peter-M Kloetzel; Elke Krüger
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-08       Impact factor: 11.205

3.  Proteasomes. A molecular census of 26S proteasomes in intact neurons.

Authors:  Shoh Asano; Yoshiyuki Fukuda; Florian Beck; Antje Aufderheide; Friedrich Förster; Radostin Danev; Wolfgang Baumeister
Journal:  Science       Date:  2015-01-23       Impact factor: 47.728

4.  Increased proteasome activity in human embryonic stem cells is regulated by PSMD11.

Authors:  David Vilchez; Leah Boyer; Ianessa Morantte; Margaret Lutz; Carsten Merkwirth; Derek Joyce; Brian Spencer; Lesley Page; Eliezer Masliah; W Travis Berggren; Fred H Gage; Andrew Dillin
Journal:  Nature       Date:  2012-09-13       Impact factor: 49.962

5.  Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

Authors:  Henrike C Besche; Zhe Sha; Nikolay V Kukushkin; Andreas Peth; Eva-Maria Hock; Woong Kim; Steven Gygi; Juan A Gutierrez; Hua Liao; Lawrence Dick; Alfred L Goldberg
Journal:  EMBO J       Date:  2014-05-08       Impact factor: 11.598

Review 6.  Molecular architecture and assembly of the eukaryotic proteasome.

Authors:  Robert J Tomko; Mark Hochstrasser
Journal:  Annu Rev Biochem       Date:  2013-03-13       Impact factor: 23.643

7.  Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97.

Authors:  Zhe Sha; Alfred L Goldberg
Journal:  Curr Biol       Date:  2014-07-03       Impact factor: 10.834

8.  Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA.

Authors:  Di Yu; Andy Hee-Meng Tan; Xin Hu; Vicki Athanasopoulos; Nicholas Simpson; Diego G Silva; Andreas Hutloff; Keith M Giles; Peter J Leedman; Kong Peng Lam; Christopher C Goodnow; Carola G Vinuesa
Journal:  Nature       Date:  2007-11-08       Impact factor: 49.962

9.  Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.

Authors:  Sooryanarayana Varambally; Qi Cao; Ram-Shankar Mani; Sunita Shankar; Xiaosong Wang; Bushra Ateeq; Bharathi Laxman; Xuhong Cao; Xiaojun Jing; Kalpana Ramnarayanan; J Chad Brenner; Jindan Yu; Jung H Kim; Bo Han; Patrick Tan; Chandan Kumar-Sinha; Robert J Lonigro; Nallasivam Palanisamy; Christopher A Maher; Arul M Chinnaiyan
Journal:  Science       Date:  2008-11-13       Impact factor: 47.728
  9 in total
  4 in total

1.  The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges.

Authors:  G R Tundo; D Sbardella; A M Santoro; A Coletta; F Oddone; G Grasso; D Milardi; P M Lacal; S Marini; R Purrello; G Graziani; M Coletta
Journal:  Pharmacol Ther       Date:  2020-05-19       Impact factor: 12.310

2.  Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells.

Authors:  Saumel Pérez-Rodriguez; Tune Wulff; Bjørn G Voldborg; Claudia Altamirano; Mauricio A Trujillo-Roldán; Norma A Valdez-Cruz
Journal:  ACS Omega       Date:  2021-05-03

3.  APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome.

Authors:  Rosanna Palumbo; Marta Gogliettino; Ennio Cocca; Roberta Iannitti; Annamaria Sandomenico; Menotti Ruvo; Marco Balestrieri; Mosè Rossi; Gianna Palmieri
Journal:  Int J Mol Sci       Date:  2016-09-23       Impact factor: 5.923

4.  Complex-centric proteome profiling by SEC-SWATH-MS.

Authors:  Moritz Heusel; Isabell Bludau; George Rosenberger; Robin Hafen; Max Frank; Amir Banaei-Esfahani; Audrey van Drogen; Ben C Collins; Matthias Gstaiger; Ruedi Aebersold
Journal:  Mol Syst Biol       Date:  2019-01-14       Impact factor: 11.429
  4 in total

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