Literature DB >> 26181830

Emerging pharmacological therapy for functional dyspepsia.

Mariko Hojo1, Akihito Nagahara2, Daisuke Asaoka2, Sumio Watanabe2.   

Abstract

Functional dyspepsia (FD) is a multifactorial disease with complex underlying pathophysiology. To date, there is no established treatment for FD. This review summarizes recent progress in pharmacological therapy for the disease. A newly developed drug, acotiamide, is expected to improve symptoms of postprandial distress syndrome. Herbal medicines are also expected to become options for FD treatment.

Entities:  

Keywords:  Acetylcholine; Acotiamide rikkunshito; Itopride; Tandospirone

Year:  2013        PMID： 26181830     DOI： 10.1007/s12328-013-0425-7

Source DB:  PubMed          Journal:  Clin J Gastroenterol        ISSN： 1865-7265


  26 in total

1.  Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs.

Authors:  Y Iwanaga; N Miyashita; T Saito; K Morikawa; Z Itoh
Journal:  Jpn J Pharmacol       Date:  1996-06

2.  Rikkunshito improves the symptoms in patients with functional dyspepsia, accompanied by an increase in the level of plasma ghrelin.

Authors:  Makoto Arai; Tomoaki Matsumura; Naoko Tsuchiya; Chiharu Sadakane; Ryouhei Inami; Takuto Suzuki; Masaharu Yoshikawa; Fumio Imazeki; Osamu Yokosuka
Journal:  Hepatogastroenterology       Date:  2012 Jan-Feb

3.  The effects of itopride on oesophageal motility and lower oesophageal sphincter function in man.

Authors:  E Scarpellini; R Vos; K Blondeau; V Boecxstaens; R Farré; A Gasbarrini; J Tack
Journal:  Aliment Pharmacol Ther       Date:  2010-10-18       Impact factor: 8.171

Review 4.  Functional gastroduodenal disorders.

Authors:  Jan Tack; Nicholas J Talley; Michael Camilleri; Gerald Holtmann; Pinjin Hu; Juan-R Malagelada; Vincenzo Stanghellini
Journal:  Gastroenterology       Date:  2006-04       Impact factor: 22.682

5.  Functional dyspepsia impacts absenteeism and direct and indirect costs.

Authors:  Richard A Brook; Nathan L Kleinman; Rok Seon Choung; Arthur K Melkonian; James E Smeeding; Nicholas J Talley
Journal:  Clin Gastroenterol Hepatol       Date:  2010-03-19       Impact factor: 11.382

6.  Effects of traditional herbal medicine on gastric mucin against ethanol-induced gastric injury in rats.

Authors:  Y Goso; Y Ogata; K Ishihara; K Hotta
Journal:  Comp Biochem Physiol C Pharmacol Toxicol Endocrinol       Date:  1996-01

7.  A placebo-controlled trial of itopride in functional dyspepsia.

Authors:  Gerald Holtmann; Nicholas J Talley; Tobias Liebregts; Birgit Adam; Christopher Parow
Journal:  N Engl J Med       Date:  2006-02-23       Impact factor: 91.245

8.  Itopride in functional dyspepsia: results of two phase III multicentre, randomised, double-blind, placebo-controlled trials.

Authors:  N J Talley; J Tack; T Ptak; R Gupta; M Giguère
Journal:  Gut       Date:  2007-10-26       Impact factor: 23.059

9.  Acotiamide hydrochloride (Z-338), a novel prokinetic agent, restores delayed gastric emptying and feeding inhibition induced by restraint stress in rats.

Authors:  K Seto; T Sasaki; K Katsunuma; N Kobayashi; K Tanaka; J Tack
Journal:  Neurogastroenterol Motil       Date:  2008-05-09       Impact factor: 3.598

10.  Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.

Authors:  Hiroshi Takeda; Chiharu Sadakane; Tomohisa Hattori; Takehiko Katsurada; Tatsuya Ohkawara; Koichi Nagai; Masahiro Asaka
Journal:  Gastroenterology       Date:  2008-02-29       Impact factor: 22.682
View more
  4 in total

1.  Comparative efficacy and acceptability of psychotropic drugs for functional dyspepsia in adults: A systematic review and network meta-analysis.

Authors:  Wan Zhou; Xia Li; Yin Huang; Xiaoxiao Xu; Yan Liu; Jiayan Wang; Gang Nie; Dongdong Zhou
Journal:  Medicine (Baltimore)       Date:  2021-05-21       Impact factor: 1.817

2.  Acupuncture and related therapies used as add-on or alternative to prokinetics for functional dyspepsia: overview of systematic reviews and network meta-analysis.

Authors:  Robin S T Ho; Vincent C H Chung; Charlene H L Wong; Justin C Y Wu; Samuel Y S Wong; Irene X Y Wu
Journal:  Sci Rep       Date:  2017-09-04       Impact factor: 4.379

3.  Electroacupuncture plus standard of care for managing refractory functional dyspepsia: protocol of a pragmatic trial with economic evaluation.

Authors:  Wai Zhu Sun; Yan Li Ju; Sheung Sheung Hung; Wai Ling Lin; Ka Chun Leung; Vincent C H Chung; Charlene H L Wong; Jessica Y L Ching; Samuel Y S Wong; Justin C Y Wu
Journal:  BMJ Open       Date:  2018-03-27       Impact factor: 2.692

Review 4.  Chinese herbal medicine for functional dyspepsia: systematic review of systematic reviews.

Authors:  Michael H K Chu; Irene X Y Wu; Robin S T Ho; Charlene H L Wong; Anthony L Zhang; Yan Zhang; Justin C Y Wu; Vincent C H Chung
Journal:  Therap Adv Gastroenterol       Date:  2018-07-16       Impact factor: 4.409
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.