Literature DB >> 20304102

Functional dyspepsia impacts absenteeism and direct and indirect costs.

Richard A Brook1, Nathan L Kleinman, Rok Seon Choung, Arthur K Melkonian, James E Smeeding, Nicholas J Talley.   

Abstract

BACKGROUND & AIMS: Functional dyspepsia (FD) is a common morbid condition but data are limited on the direct and indirect costs for employees with FD or on its impact on productivity. Few data on absenteeism and no objective information are available. This study aimed to assess the impact of FD on costs and effects on absenteeism and work output (productivity).
METHODS: We performed a retrospective analysis of payroll data and adjudicated health insurance medical and prescription claims collected over a 4-year study period (January 1, 2001 to December 31, 2004) from more than 300,000 employees. Data from employees with and without (controls) FD were compared using 2-part regression techniques. Outcome measures included medical (total and by place of service) and prescription costs, absenteeism, and objectively measured productivity output.
RESULTS: Employees with FD (N = 1669) had greater average annual medical and prescription drug costs and indirect costs (owing to sick leave and short- and long-term disability absences) than controls (N = 274,206). Compared with controls, the FD employees incurred costs that were $5138 greater and had greater costs for each place of service (all P < .0001). The employees with FD had an additional 0.83 absence days per year and produced 12% fewer units per hour than controls (both P < .05).
CONCLUSIONS: Employees with FD have greater costs at all places of service and lower productivity than employees without FD. Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20304102     DOI: 10.1016/j.cgh.2010.03.003

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN: 1542-3565            Impact factor:   11.382


  60 in total

Review 1.  Review article: current treatment options and management of functional dyspepsia.

Authors:  B E Lacy; N J Talley; G R Locke; E P Bouras; J K DiBaise; H B El-Serag; B P Abraham; C W Howden; P Moayyedi; C Prather
Journal:  Aliment Pharmacol Ther       Date:  2012-05-16       Impact factor: 8.171

2.  Geography lessons: scrutinizing state-by-state differences in inpatient gastroparesis care.

Authors:  William L Hasler
Journal:  Dig Dis Sci       Date:  2013-10       Impact factor: 3.199

3.  Excess comorbidity prevalence and cost associated with functional dyspepsia in an employed population.

Authors:  Richard A Brook; Nathan L Kleinman; Rok Seon Choung; James E Smeeding; Nicholas J Talley
Journal:  Dig Dis Sci       Date:  2011-07-13       Impact factor: 3.199

4.  Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study.

Authors:  Nicholas J Talley; G Richard Locke; Yuri A Saito; Ann E Almazar; Ernest P Bouras; Colin W Howden; Brian E Lacy; John K DiBaise; Charlene M Prather; Bincy P Abraham; Hashem B El-Serag; Paul Moayyedi; Linda M Herrick; Lawrence A Szarka; Michael Camilleri; Frank A Hamilton; Cathy D Schleck; Katherine E Tilkes; Alan R Zinsmeister
Journal:  Gastroenterology       Date:  2015-04-25       Impact factor: 22.682

5.  Effects of Antidepressants on Gastric Function in Patients with Functional Dyspepsia.

Authors:  B E Lacy; Y A Saito; M Camilleri; E Bouras; J K DiBaise; L M Herrick; L A Szarka; K Tilkes; A R Zinsmeister; N J Talley
Journal:  Am J Gastroenterol       Date:  2017-12-19       Impact factor: 10.864

Review 6.  Overlap of functional dyspepsia and GERD--diagnostic and treatment implications.

Authors:  Eamonn M M Quigley; Brian E Lacy
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-01-08       Impact factor: 46.802

7.  Gastric Contraction Imaging System Using a 3-D Endoscope.

Authors:  Kayo Yoshimoto; Kenji Yamada; Kenji Watabe; Maki Takeda; Takahiro Nishimura; Michiko Kido; Toshiaki Nagakura; Hideya Takahashi; Tsutomu Nishida; Hideki Iijima; Masahiko Tsujii; Tetsuo Takehara; Yuko Ohno
Journal:  IEEE J Transl Eng Health Med       Date:  2014-01-09       Impact factor: 3.316

8.  [Clinical practice guideline on the management of patients with dyspepsia. Update 2012].

Authors:  Javier P Gisbert; Xavier Calvet; Juan Ferrándiz; Juan Mascort; Pablo Alonso-Coello; Mercè Marzo
Journal:  Aten Primaria       Date:  2012-10-01       Impact factor: 1.137

Review 9.  Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology.

Authors:  Nicholas J Talley; Gerald Holtmann; Marjorie M Walker
Journal:  J Gastroenterol       Date:  2015-04-29       Impact factor: 7.527

Review 10.  Functional Dyspepsia: Diagnostic and Therapeutic Approaches.

Authors:  Gregory S Sayuk; C Prakash Gyawali
Journal:  Drugs       Date:  2020-09       Impact factor: 9.546

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