Literature DB >> 26178920

Therapeutic Enzyme-Responsive Nanoparticles for Targeted Delivery and Accumulation in Tumors.

Cassandra E Callmann1, Christopher V Barback2, Matthew P Thompson1, David J Hall2, Robert F Mattrey2, Nathan C Gianneschi1.   

Abstract

An enzyme-responsive, paclitaxel-loaded nanoparticle is described and assessed in vivo in a human fibrosarcoma murine xenograft. This work represents a proof-of-concept study demonstrating the utility of enzyme-responsive nanoscale drug carriers capable of targeted accumulation and retention in tumor tissue in response to overexpressed endogenous enzymes.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  drug delivery; enzyme-responsive; nanomaterials; self-assembly; stimuli-responsive

Mesh：

Substances：

Year:  2015        PMID： 26178920      PMCID： PMC4699560          DOI： 10.1002/adma.201501803

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  53 in total

1.  Enhanced antitumor activity of paclitaxel in combination with the anticarcinoma immunoconjugate BR96-doxorubicin.

Authors:  P A Trail; D Willner; A B Bianchi; A J Henderson; M D TrailSmith; E Girit; S Lasch; I Hellström; K E Hellström
Journal:  Clin Cancer Res       Date:  1999-11       Impact factor: 12.531

2.  The development of L2X2Ru=CHR olefin metathesis catalysts: an organometallic success story.

Authors:  T M Trnka; R H Grubbs
Journal:  Acc Chem Res       Date:  2001-01       Impact factor: 22.384

3.  Inhibitory effect of selenite on invasion of HT1080 tumor cells.

Authors:  S O Yoon; M M Kim; A S Chung
Journal:  J Biol Chem       Date:  2001-03-27       Impact factor: 5.157

4.  Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.

Authors:  C Bremer; S Bredow; U Mahmood; R Weissleder; C H Tung
Journal:  Radiology       Date:  2001-11       Impact factor: 11.105

5.  Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems.

Authors:  Twan Lammers; Peter Peschke; Rainer Kühnlein; Vladimir Subr; Karel Ulbrich; Peter Huber; Wim Hennink; Gert Storm
Journal:  Neoplasia       Date:  2006-10       Impact factor: 5.715

6.  Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

Authors:  Tao Jiang; Emilia S Olson; Quyen T Nguyen; Melinda Roy; Patricia A Jennings; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-15       Impact factor: 11.205

7.  Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors.

Authors:  Y Tong; W Song; R G Crystal
Journal:  Cancer Res       Date:  2001-10-15       Impact factor: 12.701

8.  Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy.

Authors:  Fabio Pastorino; Chiara Brignole; Danilo Marimpietri; Michele Cilli; Claudio Gambini; Domenico Ribatti; Renato Longhi; Theresa M Allen; Angelo Corti; Mirco Ponzoni
Journal:  Cancer Res       Date:  2003-11-01       Impact factor: 12.701

Review 9.  Nanoparticle therapeutics: an emerging treatment modality for cancer.

Authors:  Mark E Davis; Zhuo Georgia Chen; Dong M Shin
Journal:  Nat Rev Drug Discov       Date:  2008-09       Impact factor: 84.694

10.  Enzyme-directed assembly of nanoparticles in tumors monitored by in vivo whole animal imaging and ex vivo super-resolution fluorescence imaging.

Authors:  Miao-Ping Chien; Andrea S Carlini; Dehong Hu; Christopher V Barback; Anthony M Rush; David J Hall; Galya Orr; Nathan C Gianneschi
Journal:  J Am Chem Soc       Date:  2013-12-05       Impact factor: 15.419
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  36 in total

1.  Expanding the ROMP Toolbox: Synthesis of Air-Stable Benzonorbornadiene Polymers by Aryne Chemistry.

Authors:  Jose M Medina; Jeong Hoon Ko; Heather D Maynard; Neil K Garg
Journal:  Macromolecules       Date:  2017-01-04       Impact factor: 5.985

2.  Metabolite Responsive Nanoparticle-Protein Complex.

Authors:  Krista R Fruehauf; Tae Il Kim; Edward L Nelson; Joseph P Patterson; Szu-Wen Wang; Kenneth J Shea
Journal:  Biomacromolecules       Date:  2019-06-03       Impact factor: 6.988

3.  Matrix Metalloproteinase-9-Responsive Nanogels for Proximal Surface Conversion and Activated Cellular Uptake.

Authors:  Mallory R Gordon; Bo Zhao; Francesca Anson; Ann Fernandez; Khushboo Singh; Celia Homyak; Mine Canakci; Richard W Vachet; S Thayumanavan
Journal:  Biomacromolecules       Date:  2018-02-08       Impact factor: 6.988

Review 4.  Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids.

Authors:  Minjie Sun; Kaikai Wang; David Oupický
Journal:  Adv Healthc Mater       Date:  2017-12-11       Impact factor: 9.933

5.  Influenza A virus mimetic nanoparticles trigger selective cell uptake.

Authors:  Sara Maslanka Figueroa; Anika Veser; Kathrin Abstiens; Daniel Fleischmann; Sebastian Beck; Achim Goepferich
Journal:  Proc Natl Acad Sci U S A       Date:  2019-04-29       Impact factor: 11.205

6.  Balancing the intermolecular forces in peptide amphiphiles for controlling self-assembly transitions.

Authors:  C J Buettner; A J Wallace; S Ok; A A Manos; M J Nicholl; A Ghosh; M F Tweedle; J E Goldberger
Journal:  Org Biomol Chem       Date:  2017-06-21       Impact factor: 3.876

7.  Dual-responsive nanoparticles release cargo upon exposure to matrix metalloproteinase and reactive oxygen species.

Authors:  Kevin B Daniel; Cassandra E Callmann; Nathan C Gianneschi; Seth M Cohen
Journal:  Chem Commun (Camb)       Date:  2016-02-04       Impact factor: 6.222

8.  Polycatechol Nanoparticle MRI Contrast Agents.

Authors:  Yiwen Li; Yuran Huang; Zhao Wang; Fabio Carniato; Yijun Xie; Joseph P Patterson; Matthew P Thompson; Christopher M Andolina; Treffly B Ditri; Jill E Millstone; Joshua S Figueroa; Jeffrey D Rinehart; Miriam Scadeng; Mauro Botta; Nathan C Gianneschi
Journal:  Small       Date:  2015-12-17       Impact factor: 13.281

9.  Enzyme-Targeted Nanoparticles for Delivery to Ischemic Skeletal Muscle.

Authors:  J L Ungerleider; J K Kammeyer; R L Braden; K L Christman; N C Gianneschi
Journal:  Polym Chem       Date:  2017-05-24       Impact factor: 5.582

10.  Smart Nanotransformers with Unique Enzyme-Inducible Structural Changes and Drug Release Properties.

Authors:  Vanessa Bellat; Hyun Hee Lee; Linda Vahdat; Benedict Law
Journal:  Biomacromolecules       Date:  2016-05-24       Impact factor: 6.988
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