Literature DB >> 26169737

Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility.

David Bitto1, David J Harvey, Steinar Halldorsson, Katie J Doores, Laura K Pritchard, Juha T Huiskonen, Thomas A Bowden, Max Crispin.   

Abstract

Glycan analysis of virion-derived glycoproteins is challenging due to the difficulties in glycoprotein isolation and low sample abundance. Here, we describe how ion mobility mass spectrometry can be used to obtain spectra from virion samples. We also describe how negative ion fragmentation of glycans can be used to probe structural features of virion glycans.

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Year:  2015        PMID: 26169737      PMCID: PMC4817836          DOI: 10.1007/978-1-4939-2874-3_7

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  42 in total

1.  The ribonucleic acids of Uukuniemi virus, a noncubical tick-borne arbovirus.

Authors:  R Pettersson; L Kääriäinen
Journal:  Virology       Date:  1973-12       Impact factor: 3.616

2.  GlycoMod--a software tool for determining glycosylation compositions from mass spectrometric data.

Authors:  C A Cooper; E Gasteiger; N H Packer
Journal:  Proteomics       Date:  2001-02       Impact factor: 3.984

3.  Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.

Authors:  Kabamba B Alexandre; Elin S Gray; Bronwen E Lambson; Penny L Moore; Isaac A Choge; Koleka Mlisana; Salim S Abdool Karim; James McMahon; Barry O'Keefe; Rachel Chikwamba; Lynn Morris
Journal:  Virology       Date:  2010-04-13       Impact factor: 3.616

4.  Fragmentation of negative ions from carbohydrates: part 2. Fragmentation of high-mannose N-linked glycans.

Authors:  David J Harvey
Journal:  J Am Soc Mass Spectrom       Date:  2005-05       Impact factor: 3.109

5.  Fragmentation of negative ions from carbohydrates: part 1. Use of nitrate and other anionic adducts for the production of negative ion electrospray spectra from N-linked carbohydrates.

Authors:  David J Harvey
Journal:  J Am Soc Mass Spectrom       Date:  2005-05       Impact factor: 3.109

6.  Stabilization of sialic acids in N-linked oligosaccharides and gangliosides for analysis by positive ion matrix-assisted laser desorption/ionization mass spectrometry.

Authors:  A K Powell; D J Harvey
Journal:  Rapid Commun Mass Spectrom       Date:  1996       Impact factor: 2.419

7.  Derivatization of sialic acids for stabilization in matrix-assisted laser desorption/ionization mass spectrometry and concomitant differentiation of alpha(2 --> 3)- and alpha(2 --> 6)-isomers.

Authors:  Susan F Wheeler; Paula Domann; David J Harvey
Journal:  Rapid Commun Mass Spectrom       Date:  2009-01       Impact factor: 2.419

8.  Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.

Authors:  David J Harvey; Anthony H Merry; Louise Royle; Matthew P Campbell; Raymond A Dwek; Pauline M Rudd
Journal:  Proteomics       Date:  2009-08       Impact factor: 3.984

9.  Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

Authors:  Laura M Walker; Sanjay K Phogat; Po-Ying Chan-Hui; Denise Wagner; Pham Phung; Julie L Goss; Terri Wrin; Melissa D Simek; Steven Fling; Jennifer L Mitcham; Jennifer K Lehrman; Frances H Priddy; Ole A Olsen; Steven M Frey; Phillip W Hammond; Stephen Kaminsky; Timothy Zamb; Matthew Moyle; Wayne C Koff; Pascal Poignard; Dennis R Burton
Journal:  Science       Date:  2009-09-03       Impact factor: 47.728

10.  Dimeric architecture of the Hendra virus attachment glycoprotein: evidence for a conserved mode of assembly.

Authors:  Thomas A Bowden; Max Crispin; David J Harvey; E Yvonne Jones; David I Stuart
Journal:  J Virol       Date:  2010-04-07       Impact factor: 5.103

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  5 in total

1.  Structural Studies of Fucosylated N-Glycans by Ion Mobility Mass Spectrometry and Collision-Induced Fragmentation of Negative Ions.

Authors:  David J Harvey; Weston B Struwe
Journal:  J Am Soc Mass Spectrom       Date:  2018-05-22       Impact factor: 3.109

Review 2.  Glycosylation profiling to evaluate glycoprotein immunogens against HIV-1.

Authors:  Anna-Janina Behrens; Weston B Struwe; Max Crispin
Journal:  Expert Rev Proteomics       Date:  2017-09-14       Impact factor: 3.940

3.  Separation of Sialylated Glycan Isomers by Differential Mobility Spectrometry.

Authors:  Catherine S Lane; Kirsty McManus; Philip Widdowson; Sarah A Flowers; Gerard Powell; Ian Anderson; J Larry Campbell
Journal:  Anal Chem       Date:  2019-07-08       Impact factor: 6.986

4.  Formation and fragmentation of doubly and triply charged ions in the negative ion spectra of neutral N-glycans from viral and other glycoproteins.

Authors:  David J Harvey; Weston B Struwe; Anna-Janina Behrens; Snezana Vasiljevic; Max Crispin
Journal:  Anal Bioanal Chem       Date:  2021-08-03       Impact factor: 4.142

5.  Identification of N-glycans with GalNAc-containing antennae from recombinant HIV trimers by ion mobility and negative ion fragmentation.

Authors:  David J Harvey; Anna-Janina Behrens; Max Crispin; Weston B Struwe
Journal:  Anal Bioanal Chem       Date:  2021-07-30       Impact factor: 4.142

  5 in total

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