Lina Ma1, Yun Li2, Jieyu Wang3. 1. Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: marina0583@163.com. 2. Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: liyunxw@163.com. 3. Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: wang_jie_yu@sina.com.
Abstract
OBJECTIVES: This review aims to clarify the relationship between telomeres and essential hypertension. DESIGN AND METHODS: A PubMed search and a critical review were performed relating to studies about the clinical and biological relevance of telomeres in essential hypertension. RESULTS: Telomeres and telomerase activity play an important role in the occurrence and development of hypertension in both animal and human studies. CONCLUSIONS: A more complete understanding of the molecular mechanisms underlying the development of hypertension could reduce the incidence of hypertension-related diseases.
OBJECTIVES: This review aims to clarify the relationship between telomeres and essential hypertension. DESIGN AND METHODS: A PubMed search and a critical review were performed relating to studies about the clinical and biological relevance of telomeres in essential hypertension. RESULTS: Telomeres and telomerase activity play an important role in the occurrence and development of hypertension in both animal and human studies. CONCLUSIONS: A more complete understanding of the molecular mechanisms underlying the development of hypertension could reduce the incidence of hypertension-related diseases.
Authors: Sheng-Nan Yu; Shi-Qi Chen; Guo-Quan Fan; Wei-Zhe Pan; Jin Jia; Qian Wang; Li Ma; Ben Li; Mei Qiang; Yu-Lan Qiu; Tong Wang Journal: Biomed Res Int Date: 2020-12-03 Impact factor: 3.411
Authors: Olga V Zimnitskaya; Marina M Petrova; Natalia V Lareva; Marina S Cherniaeva; Mustafa Al-Zamil; Anastasia E Ivanova; Natalia A Shnayder Journal: Genes (Basel) Date: 2022-07-12 Impact factor: 4.141
Authors: Dhuha M B AlDehaini; Suzanne A Al-Bustan; Zainab Hasan Abdulla Malalla; Muhalab E Ali; Mai Sater; Hayder A Giha Journal: Cardiovasc Endocrinol Metab Date: 2020-09-03
Authors: Ewa Gutmajster; Jerzy Chudek; Aleksandra Augusciak-Duma; Malgorzata Szwed; Aleksandra Szybalska; Malgorzata Mossakowska; Monika Puzianowska-Kuznicka; Andrzej Wiecek; Aleksander L Sieron Journal: J Appl Genet Date: 2018-06-25 Impact factor: 3.240