Literature DB >> 26168592

Buyer Beware: Pitfalls in Toxicology Laboratory Testing.

D Adam Algren, Michael R Christian.   

Abstract

Urine drug screens are commonly used in various clinical settings and situations. Immunoassays are the most commonly available method of testing for urine drug screens in hospitals. Although convenient, immunoassays are prone to false positive and false negative results. It is important for the health care provider to understand the principles of the laboratory methods involved with urine drug screens as this will help guide appropriate result interpretation and therefore improve clinical care.

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Year:  2015        PMID: 26168592      PMCID: PMC6170116     

Source DB:  PubMed          Journal:  Mo Med        ISSN: 0026-6620


  28 in total

1.  Utility of routine drug screening in a psychiatric emergency setting.

Authors:  M J Schiller; M Shumway; S L Batki
Journal:  Psychiatr Serv       Date:  2000-04       Impact factor: 3.084

2.  Utility of toxicology screening in a pediatric emergency department.

Authors:  J M Sugarman; G C Rodgers; R I Paul
Journal:  Pediatr Emerg Care       Date:  1997-06       Impact factor: 1.454

3.  False-positive phencyclidine immunoassay results caused by 3,4-methylenedioxypyrovalerone (MDPV).

Authors:  Abe M Macher; Thomas M Penders
Journal:  Drug Test Anal       Date:  2012-05-20       Impact factor: 3.345

4.  Nonfatal tramadol overdose may cause false-positive phencyclidine on Emit-II assay.

Authors:  Andrew M King; Jennifer L Pugh; Nathan B Menke; Matthew D Krasowski; Michael J Lynch; Anthony F Pizon
Journal:  Am J Emerg Med       Date:  2012-08-31       Impact factor: 2.469

5.  Urine drug screens in overdose patients do not contribute to immediate clinical management.

Authors:  R E Montague; R F Grace; J H Lewis; G M Shenfield
Journal:  Ther Drug Monit       Date:  2001-02       Impact factor: 3.681

6.  Scientific issues in drug testing. Council on Scientific Affairs.

Authors: 
Journal:  JAMA       Date:  1987-06-12       Impact factor: 56.272

7.  False-positive urine phencyclidine immunoassay screen result caused by interference by tramadol and its metabolites.

Authors:  Binh T Ly; Stephen L Thornton; Colleen Buono; Judith A Stone; Alan H B Wu
Journal:  Ann Emerg Med       Date:  2011-09-15       Impact factor: 5.721

8.  Rapid urine drug screens: diphenhydramine and methadone cross-reactivity.

Authors:  Steven C Rogers; Charles W Pruitt; Dennis J Crouch; E Martin Caravati
Journal:  Pediatr Emerg Care       Date:  2010-09       Impact factor: 1.454

9.  Cross-reactivity studies and predictive modeling of "Bath Salts" and other amphetamine-type stimulants with amphetamine screening immunoassays.

Authors:  M Petrie; K L Lynch; S Ekins; J S Chang; R J Goetz; A H B Wu; M D Krasowski
Journal:  Clin Toxicol (Phila)       Date:  2013-02       Impact factor: 4.467

Review 10.  Urine drug testing in pain medicine.

Authors:  Howard A Heit; Douglas L Gourlay
Journal:  J Pain Symptom Manage       Date:  2004-03       Impact factor: 3.612

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  1 in total

1.  The effect of contextual information on decision-making in forensic toxicology.

Authors:  Hilary J Hamnett; Itiel E Dror
Journal:  Forensic Sci Int       Date:  2020-06-30       Impact factor: 2.395

  1 in total

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