Literature DB >> 26165467

MicroRNAs in Renal Cell Carcinoma.

Donald F Sellitti1, Sonia Q Doi.   

Abstract

New therapies based on the targeting of signal pathways (such as VHL/HIF-1) common to most renal cell carcinomas (RCC), have greatly improved the outlook for sufferers of this disease. Given the growing reputation of many microRNAs (miRNAs) as both tumor suppressors and oncogenes, the measurement and manipulation of these small nucleotides in RCC patients may provide yet another valuable advance in renal cancer diagnosis and treatment. The present review summarizes the current literature on the role of microRNAs in RCC development and progression emphasizing the interaction of specific miRNAs with both oncogenic and tumor suppressor pathways of particular importance in renal cancer.

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Year:  2015        PMID： 26165467     DOI： 10.2174/2211536604666150713105247

Source DB:  PubMed          Journal:  Microrna


  11 in total

1.  Comparison of exosomal microRNAs secreted by 786-O clear cell renal carcinoma cells and HK-2 proximal tubule-derived cells in culture identifies microRNA-205 as a potential biomarker of clear cell renal carcinoma.

Authors:  Victor C Crentsil; Hui Liu; Donald F Sellitti
Journal:  Oncol Lett       Date:  2018-05-21       Impact factor: 2.967

Review 2.  The epigenetic landscape of renal cancer.

Authors:  Mark R Morris; Farida Latif
Journal:  Nat Rev Nephrol       Date:  2016-11-28       Impact factor: 28.314

3.  MiR-200a with CDC7 as a direct target declines cell viability and promotes cell apoptosis in Wilm's tumor via Wnt/β-catenin signaling pathway.

Authors:  Xiu-Ling Liang; Yu-Long Wang; Pei-Rong Wang
Journal:  Mol Cell Biochem       Date:  2021-02-18       Impact factor: 3.396

4.  miR-211 promotes lens epithelial cells apoptosis by targeting silent mating-type information regulation 2 homolog 1 in age-related cataracts.

Authors:  Bo Lu; Ian T Christensen; Li-Wei Ma; Xin-Ling Wang; Ling-Feng Jiang; Chun-Xia Wang; Li Feng; Jin-Song Zhang; Qi-Chang Yan
Journal:  Int J Ophthalmol       Date:  2018-02-18       Impact factor: 1.779

5.  A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

Authors:  Elke Nolte; Sven Wach; Izabella Thais Silva; Sabine Lukat; Arif B Ekici; Jennifer Munkert; Frieder Müller-Uri; Wolfgang Kreis; Cláudia Maria Oliveira Simões; Julio Vera; Bernd Wullich; Helge Taubert; Xin Lai
Journal:  Oncotarget       Date:  2017-02-14

6.  miR-502-mediated histone methyltransferase SET8 expression is associated with clear cell renal cell carcinoma risk.

Authors:  Shenglei Zhang; Zhanjun Guo; Jinsheng Xu; Jing Wang; Junxia Zhang; Liwen Cui; Huiran Zhang; Yueping Liu; Yaling Bai
Journal:  Oncol Lett       Date:  2017-10-02       Impact factor: 2.967

7.  Expression of microRNA-3133 correlates with the prognosis in patients with clear cell renal cell carcinoma.

Authors:  Xiaoyan Chen
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

8.  Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2.

Authors:  Lu Chen; Le Chen; Zhiyuan Qin; Jinxiu Lei; Sheng Ye; Kui Zeng; Hua Wang; Meidan Ying; Jianqing Gao; Su Zeng; Lushan Yu
Journal:  Acta Pharm Sin B       Date:  2019-01-08       Impact factor: 11.413

9.  FRTL-5 Rat Thyroid Cells Release Thyroglobulin Sequestered in Exosomes: A Possible Novel Mechanism for Thyroglobulin Processing in the Thyroid.

Authors:  Pavel Vlasov; Sonia Q Doi; Donald F Sellitti
Journal:  J Thyroid Res       Date:  2016-06-09

10.  MiR-106a-5p inhibits the cell migration and invasion of renal cell carcinoma through targeting PAK5.

Authors:  Yao-Jie Pan; Lu-Lu Wei; Xiao-Jin Wu; Fu-Chun Huo; Jie Mou; Dong-Sheng Pei
Journal:  Cell Death Dis       Date:  2017-10-26       Impact factor: 8.469
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