Literature DB >> 26163217

Gamma-carboline inhibits neurodegenerative processes in a transgenic model of amyotrophic lateral sclerosis.

E V Bronovitsky1, A V Deikin, T G Ermolkevich, A B Elyakov, E N Fedorov, E R Sadchikova, I L Goldman, R K Ovchinnikov, A Yu Roman, I V Khritankova, M S Kukharsky, V L Buchman, S O Bachurin, A A Ustyugov.   

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Year:  2015        PMID： 26163217     DOI： 10.1134/S1607672915030138

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


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  12 in total

1.  Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds.

Authors:  S O Bachurin; A A Ustyugov; O Peters; T A Shelkovnikova; V L Buchman; N N Ninkina
Journal:  Dokl Biochem Biophys       Date:  2009 Sep-Oct       Impact factor: 0.788

Review 2.  Modelling FUSopathies: focus on protein aggregation.

Authors:  Tatyana A Shelkovnikova
Journal:  Biochem Soc Trans       Date:  2013-12       Impact factor: 5.407

3.  FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein.

Authors:  T A Shelkovnikova; A A Ustyugov; A P Smirnov; V I Skvortsova; V L Buchman; S O Bachurin; N N Ninkina
Journal:  Dokl Biochem Biophys       Date:  2011-07-03       Impact factor: 0.788

Review 4.  [Modeling of lateral amyotrophic sclerosis: a transgenic method].

Authors:  S O Bachurin; N N Ninkina; T V Tarasova; T V Shelkovnikova; E A Kovrazhkina; A P Smirnov; O D Razinskaia; V I Skvortsova
Journal:  Zh Nevrol Psikhiatr Im S S Korsakova       Date:  2013

5.  Chronic administration of dimebon ameliorates pathology in TauP301S transgenic mice.

Authors:  Owen M Peters; Natalie Connor-Robson; Vladimir B Sokolov; Alexey Yu Aksinenko; Michail S Kukharsky; Sergey O Bachurin; Natalia Ninkina; Vladimir L Buchman
Journal:  J Alzheimers Dis       Date:  2013       Impact factor: 4.472

Review 6.  [Proteinopathies--forms of neurodegenerative disorders with protein aggregation-based pathology].

Authors:  T A Shelkovnikova; A A Kulikova; F O Tsvetkov; O Peters; S O Bachurin; V L Bukhman; N N Ninkina
Journal:  Mol Biol (Mosk)       Date:  2012 May-Jun

7.  Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.

Authors:  Sergey O Bachurin; Tatyana A Shelkovnikova; Alexey A Ustyugov; Owen Peters; Ina Khritankova; Marina A Afanasieva; Tatyana V Tarasova; Igor I Alentov; Vladimir L Buchman; Natalia N Ninkina
Journal:  Neurotox Res       Date:  2011-12-17       Impact factor: 3.911

8.  Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.

Authors:  Tatyana A Shelkovnikova; Hannah K Robinson; Natalie Connor-Robson; Vladimir L Buchman
Journal:  Cell Cycle       Date:  2013-09-04       Impact factor: 4.534

9.  Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.

Authors:  Tatyana A Shelkovnikova; Owen M Peters; Alexey V Deykin; Natalie Connor-Robson; Hannah Robinson; Alexey A Ustyugov; Sergey O Bachurin; Tatyana G Ermolkevich; Igor L Goldman; Elena R Sadchikova; Elena A Kovrazhkina; Veronica I Skvortsova; Shuo-Chien Ling; Sandrine Da Cruz; Philippe A Parone; Vladimir L Buchman; Natalia N Ninkina
Journal:  J Biol Chem       Date:  2013-07-18       Impact factor: 5.157

Review 10.  Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.

Authors:  P R Bharadwaj; K A Bates; T Porter; E Teimouri; G Perry; J W Steele; S Gandy; D Groth; R N Martins; Giuseppe Verdile
Journal:  Transl Psychiatry       Date:  2013-12-03       Impact factor: 6.222
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  3 in total

Review 1.  Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).

Authors:  Aleksey Ustyugov; Elena Shevtsova; Sergey Bachurin
Journal:  Mol Neurobiol       Date:  2015-06-30       Impact factor: 5.590

2.  Gamma-Carbolines Derivatives As Promising Agents for the Development of Pathogenic Therapy for Proteinopathy.

Authors:  V I Skvortsova; S O Bachurin; A A Ustyugov; M S Kukharsky; A V Deikin; V L Buchman; N N Ninkina
Journal:  Acta Naturae       Date:  2018 Oct-Dec       Impact factor: 1.845

3.  A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice.

Authors:  Kirill Chaprov; Alexander Rezvykh; Sergei Funikov; Tamara A Ivanova; Ekaterina A Lysikova; Alexei V Deykin; Michail S Kukharsky; Alexey Yu Aksinenko; Sergey O Bachurin; Natalia Ninkina; Vladimir L Buchman
Journal:  CNS Neurosci Ther       Date:  2021-03-23       Impact factor: 5.243
  3 in total

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