Literature DB >> 26159499

Clostridium difficile infections before and during use of ultraviolet disinfection.

Aarathi Nagaraja1, Paul Visintainer2, Janet P Haas3, Jonathan Menz4, Gary P Wormser1, Marisa A Montecalvo5.   

Abstract

BACKGROUND: We previously reported a significant decrease in hospital-acquired (HA) Clostridium difficile infection (CDI) coincident with the introduction of pulsed xenon ultraviolet light for room disinfection (UVD). The purpose of this study was to evaluate CDI cases in greater detail to understand the effect of UVD.
METHODS: CDI rates (HA and community acquired [CA]), CDI patient length of stay, room occupancy, and number of days between a CDI case in a room and an HA CDI case in the same room were studied for the first year of UVD compared with the 1-year period pre-UVD.
RESULTS: Compared with pre-UVD, during UVD, HA CDI was 22% less (P = .06). There was a 70% decrease for the adult intensive care units (ICUs) (P < .001), where the percentage of room discharges with UVD was greater (P < .001). During UVD, CA CDI increased by 18%, and length of stay of all CDI cases was lower because of the greater proportion of CA CDI. No significant difference was found in days to HA CDI in rooms with a prior CDI occupant.
CONCLUSION: These data suggest that UVD contributed to a reduction in ICU-acquired CDI where UVD was used for a larger proportion of discharges. Evaluation of UVD should include data for hospitalized CA CDI cases because these cases may impact the HA CDI rate.
Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Clostridium difficile; Hospital acquired; Ultraviolet disinfection

Mesh:

Substances:

Year:  2015        PMID: 26159499     DOI: 10.1016/j.ajic.2015.05.003

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  16 in total

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Authors:  Zachary A Rubin; Elise M Martin; Paul Allyn
Journal:  Curr Infect Dis Rep       Date:  2018-06-29       Impact factor: 3.725

2.  Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).

Authors:  L Clifford McDonald; Dale N Gerding; Stuart Johnson; Johan S Bakken; Karen C Carroll; Susan E Coffin; Erik R Dubberke; Kevin W Garey; Carolyn V Gould; Ciaran Kelly; Vivian Loo; Julia Shaklee Sammons; Thomas J Sandora; Mark H Wilcox
Journal:  Clin Infect Dis       Date:  2018-03-19       Impact factor: 9.079

3.  Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study.

Authors:  Deverick J Anderson; Luke F Chen; David J Weber; Rebekah W Moehring; Sarah S Lewis; Patricia F Triplett; Michael Blocker; Paul Becherer; J Conrad Schwab; Lauren P Knelson; Yuliya Lokhnygina; William A Rutala; Hajime Kanamori; Maria F Gergen; Daniel J Sexton
Journal:  Lancet       Date:  2017-01-17       Impact factor: 79.321

4.  Preventable Patient Harm: a Multidisciplinary, Bundled Approach to Reducing Clostridium difficile Infections While Using a Glutamate Dehydrogenase/Toxin Immunochromatographic Assay/Nucleic Acid Amplification Test Diagnostic Algorithm.

Authors:  Katherine Schultz; Emily Sickbert-Bennett; Ashley Marx; David J Weber; Lauren M DiBiase; Stacy Campbell-Bright; Lauren E Bode; Mike Baker; Tom Belhorn; Mark Buchanan; Sherie Goldbach; Jacci Harden; Emily Hoke; Beth Huenniger; Jonathan J Juliano; Michael Langston; Heather Ritchie; William A Rutala; Jason Smith; Shelley Summerlin-Long; Lisa Teal; Peter Gilligan
Journal:  J Clin Microbiol       Date:  2018-08-27       Impact factor: 5.948

5.  Portable pulsed xenon ultraviolet light disinfection in a teaching hospital animal laboratory in China.

Authors:  Jing-Jing Li; Shan-Ni Wang; Jiao-Jiao Qiao; Li-Hua Chen; Yu Li; Yong Wu; Yan-Xia Ding; Mei-Mei Wang; Yun Tian; Yun-Bo Liu; Chen Yan; Chen Zhang; Chang-Qing Gao
Journal:  J Photochem Photobiol B       Date:  2020-04-06       Impact factor: 6.252

Review 6.  Portable Ultraviolet Light Surface-Disinfecting Devices for Prevention of Hospital-Acquired Infections: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2018-02-07

Review 7.  Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals.

Authors:  John M Boyce
Journal:  Antimicrob Resist Infect Control       Date:  2016-04-11       Impact factor: 4.887

8.  Bactericidal effects of deep ultraviolet light-emitting diode for solutions during intravenous infusion.

Authors:  Sachiko Omotani; Katsuji Tani; Mai Aoe; Seiji Esaki; Katsuhito Nagai; Yasutoshi Hatsuda; Junji Mukai; Hitomi Teramachi; Michiaki Myotoku
Journal:  Int J Med Sci       Date:  2018-01-01       Impact factor: 3.738

9.  Global burden of Clostridium difficile infections: a systematic review and meta-analysis.

Authors:  Evelyn Balsells; Ting Shi; Callum Leese; Iona Lyell; John Burrows; Camilla Wiuff; Harry Campbell; Moe H Kyaw; Harish Nair
Journal:  J Glob Health       Date:  2019-06       Impact factor: 4.413

Review 10.  Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.

Authors:  David J Weber; William A Rutala; Deverick J Anderson; Luke F Chen; Emily E Sickbert-Bennett; John M Boyce
Journal:  Am J Infect Control       Date:  2016-05-02       Impact factor: 2.918

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