Literature DB >> 26154011

Reigning in regulatory T-cell function.

Catherine Konopacki1, George Plitas2, Alexander Rudensky1.   

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Year:  2015        PMID： 26154011     DOI： 10.1038/nbt.3285

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  14 in total

1.  Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.

Authors:  Michele W L Teng; Shin Foong Ngiow; Bianca von Scheidt; Nicole McLaughlin; Tim Sparwasser; Mark J Smyth
Journal:  Cancer Res       Date:  2010-10-05       Impact factor: 12.701

2.  T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-β1 cytokine.

Authors:  Moses K Donkor; Abira Sarkar; Peter A Savage; Ruth A Franklin; Linda K Johnson; Achim A Jungbluth; James P Allison; Ming O Li
Journal:  Immunity       Date:  2011-07-14       Impact factor: 31.745

3.  Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.

Authors:  Julia Cuende; Stéphanie Liénart; Olivier Dedobbeleer; Bas van der Woning; Gitte De Boeck; Julie Stockis; Caroline Huygens; Didier Colau; Joan Somja; Philippe Delvenne; Muriel Hannon; Frédéric Baron; Laure Dumoutier; Jean-Christophe Renauld; Hans De Haard; Michael Saunders; Pierre G Coulie; Sophie Lucas
Journal:  Sci Transl Med       Date:  2015-04-22       Impact factor: 17.956

4.  Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8.

Authors:  Justin P Edwards; Angela M Thornton; Ethan M Shevach
Journal:  J Immunol       Date:  2014-08-15       Impact factor: 5.422

5.  Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation.

Authors:  Ilona Gutcher; Moses K Donkor; Qian Ma; Alexander Y Rudensky; Richard A Flavell; Ming O Li
Journal:  Immunity       Date:  2011-03-25       Impact factor: 31.745

Review 6.  TGFbeta in Cancer.

Authors:  Joan Massagué
Journal:  Cell       Date:  2008-07-25       Impact factor: 41.582

7.  Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.

Authors:  Justin P Edwards; Hodaka Fujii; Angela X Zhou; John Creemers; Derya Unutmaz; Ethan M Shevach
Journal:  J Immunol       Date:  2013-05-03       Impact factor: 5.422

8.  Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation.

Authors:  John J Worthington; Aoife Kelly; Catherine Smedley; David Bauché; Simon Campbell; Julien C Marie; Mark A Travis
Journal:  Immunity       Date:  2015-05-12       Impact factor: 31.745

9.  Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma.

Authors:  John C Morris; Antoinette R Tan; Thomas E Olencki; Geoffrey I Shapiro; Bruce J Dezube; Michael Reiss; Frank J Hsu; Jay A Berzofsky; Donald P Lawrence
Journal:  PLoS One       Date:  2014-03-11       Impact factor: 3.240

Review 10.  'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation.

Authors:  Yisong Y Wan; Richard A Flavell
Journal:  Immunol Rev       Date:  2007-12       Impact factor: 12.988
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  1 in total

1.  Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody.

Authors:  Tao Dao; Sung Soo Mun; Andrew C Scott; Casey A Jarvis; Tatyana Korontsvit; Zhiyuan Yang; Lianxing Liu; Martin G Klatt; Manuel Guerreiro; Annamalai Selvakumar; Elliott J Brea; Claire Oh; Cheng Liu; David A Scheinberg
Journal:  Oncoimmunology       Date:  2019-04-15       Impact factor: 8.110
  1 in total

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