Zhibin Gao1, Kenzo Hiroshima2, Xiaodong Wu3, Jixian Zhang3, Dichu Shao4, Huajiang Shao5, Hanqing Yang6, Toshikazu Yusa7, Takako Kiyokawa8, Makio Kobayashi9, Yasushi Shinohara10, Oluf D Røe11,12,13, Xing Zhang14, Kenji Morinaga15. 1. Department of Pathology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China. 2. Department of Pathology, Tokyo Women's Medical University, Yachiyo Medical Center, Owada-Shinden 477-96, Yachiyo, Chiba, 276-8524, Japan. 3. Department of Respiratory Medicine, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China. 4. Yuyao Center for Disease Control and Prevention, Yangmingdong Road 129, Yuyao, Ningbo, Zhejiang Province, 315400, China. 5. Department of Gynecology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province 315400, China. 6. Department of Radiology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China. 7. Department of General Thoracic Surgery and Asbestos Disease Center, Chiba Rosai Hospital, Tatsumidaihigashi 2-16, Ichihara, Chiba, 290-0003, Japan. 8. Department of Pathology, Jikei University School of Medicine, Nishi-sinbashi 3-25-8, Minato-ku, Tokyo, Japan. 9. Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan, Kawada-cho 8-1, Shinjuku-ku, Tokyo, 162-8666, Japan. 10. Work Environment Research Group, National Institute of Occupational Safety and Health, Nagao 6-21-1, Tama-ku, Kawasaki-shi, Kanagawa, 214-8585, Japan. 11. Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Erling Skjalgssons gt. 1, Trondheim, 7491, Norway. 12. CancerClinic, Levanger Hospital, Nord-Trøndelag Hospital Trust, Kirkegata 2, 7600, Levanger, Norway. 13. Department of Oncology, Clinical Cancer Research Center, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark. 14. Zhejiang Academy of Medical Sciences, Tianmushan Road 182, Hangzhou, Zhejiang Province, 310013, China. 15. Department of Asbestos-related Health Damage Relief, Environmental Restoration and Conservation Agency of Japan, Muza Kawasaki Central Tower, Omiya-cho 1310, Saiwai-Ku, Kawasaki-Shi, Kanagawa, 212-8554, Japan.
Abstract
BACKGROUND: Chrysotile had been used in asbestos textile workshops in Southeast China but a clear relation to mesothelioma is lacking. METHODS: All patients diagnosed with mesothelioma from 2003 to 2010 at Yuyao People's Hospital were re-evaluated by multiple expert pathologists with immunohistochemistry and asbestos exposure data were collected. RESULTS: Of 43 patients with a mesothelioma diagnosis, 19 peritoneal and nine pleural cases were finally diagnosed as mesothelioma. All were females, and the mean age of the patients with peritoneal or pleural mesothelioma was 52.4 and 58.2 years, respectively. All these cases had a history of domestic or occupational exposure to chrysotile. Two-thirds of the patients were from two adjoining towns with multiple small asbestos textile workshops. Contamination of tremolite was estimated to be less than 0.3%. CONCLUSIONS: This is a report of mesothelioma in women exposed to chrysotile asbestos at home and at work, with an over-representation of peritoneal mesothelioma.
BACKGROUND: Chrysotile had been used in asbestos textile workshops in Southeast China but a clear relation to mesothelioma is lacking. METHODS: All patients diagnosed with mesothelioma from 2003 to 2010 at Yuyao People's Hospital were re-evaluated by multiple expert pathologists with immunohistochemistry and asbestos exposure data were collected. RESULTS: Of 43 patients with a mesothelioma diagnosis, 19 peritoneal and nine pleural cases were finally diagnosed as mesothelioma. All were females, and the mean age of the patients with peritoneal or pleural mesothelioma was 52.4 and 58.2 years, respectively. All these cases had a history of domestic or occupational exposure to chrysotile. Two-thirds of the patients were from two adjoining towns with multiple small asbestos textile workshops. Contamination of tremolite was estimated to be less than 0.3%. CONCLUSIONS: This is a report of mesothelioma in women exposed to chrysotile asbestos at home and at work, with an over-representation of peritoneal mesothelioma.
Authors: Manuela Valenzuela; Margarita Giraldo; Sonia Gallo-Murcia; Juliana Pineda; Laura Santos; Juan Pablo Ramos-Bonilla Journal: Curr Environ Health Rep Date: 2016-12
Authors: Yali Zeng; Yan Cui; Ji Ma; Tingting Huo; Faqin Dong; Qingbi Zhang; Jianjun Deng; Xu Zhang; Jie Yang; Yulin Wang Journal: Environ Sci Pollut Res Int Date: 2017-09-29 Impact factor: 4.223
Authors: Daniela Marsili; Benedetto Terracini; Vilma S Santana; Juan Pablo Ramos-Bonilla; Roberto Pasetto; Agata Mazzeo; Dana Loomis; Pietro Comba; Eduardo Algranti Journal: Int J Environ Res Public Health Date: 2016-05-12 Impact factor: 3.390