Literature DB >> 26145713

Food specific oral immunotherapy: a potential treatment for food allergy.

Allison J Burbank1, Wesley Burks.   

Abstract

Food allergy is a potentially life-threatening condition affecting up to 8% of children and up to 2% of adults in westernized countries. There are currently no approved treatments for food allergy apart from avoidance. The apparent increase in incidence of food allergies over the past few decades calls attention to the need for effective, disease-modifying therapies for food allergies. Oral immunotherapy (OIT) is a promising experimental treatment in which food allergic patients consume increasing quantities of food in attempt to increase their threshold for allergic reaction. Studies are ongoing to determine whether OIT is capable of safely inducing not only desensitization but also tolerance to the allergenic foods. This article focuses on recent relevant studies of OIT for the treatment of common food allergies.

Entities:  

Keywords:  desensitization; double blind placebo-controlled food challenge; food allergy; omalizumab; oral immunotherapy; probiotic; sustained unresponsiveness; tolerance

Mesh:

Year:  2015        PMID: 26145713     DOI: 10.1586/17474124.2015.1065177

Source DB:  PubMed          Journal:  Expert Rev Gastroenterol Hepatol        ISSN: 1747-4124            Impact factor:   3.869


  7 in total

Review 1.  Balancing Tolerance or Allergy to Food Proteins.

Authors:  Paul J Bryce
Journal:  Trends Immunol       Date:  2016-09-03       Impact factor: 16.687

Review 2.  Eosinophilic esophagitis during sublingual and oral allergen immunotherapy.

Authors:  Joseph Cafone; Peter Capucilli; David A Hill; Jonathan M Spergel
Journal:  Curr Opin Allergy Clin Immunol       Date:  2019-08

Review 3.  Food Allergy: Our Evolving Understanding of Its Pathogenesis, Prevention, and Treatment.

Authors:  Onyinye I Iweala; A Wesley Burks
Journal:  Curr Allergy Asthma Rep       Date:  2016-05       Impact factor: 4.806

Review 4.  The Role of Eosinophils in Immunotherapy.

Authors:  Joseph Cafone; Melanie A Ruffner; Jonathan M Spergel
Journal:  Curr Allergy Asthma Rep       Date:  2020-01-07       Impact factor: 4.919

5.  High-dose wogonin exacerbates DSS-induced colitis by up-regulating effector T cell function and inhibiting Treg cell.

Authors:  Weiming Xiao; Min Yin; Keyan Wu; Guotao Lu; Bin Deng; Yu Zhang; Li Qian; Xiaoqing Jia; Yanbing Ding; Weijuan Gong
Journal:  J Cell Mol Med       Date:  2016-09-19       Impact factor: 5.310

6.  Anti-Allergic Compounds from the Deep-Sea-Derived Actinomycete Nesterenkonia flava MCCC 1K00610.

Authors:  Chun-Lan Xie; Qingmei Liu; Jin-Mei Xia; Yuanyuan Gao; Quan Yang; Zong-Ze Shao; Guangming Liu; Xian-Wen Yang
Journal:  Mar Drugs       Date:  2017-03-14       Impact factor: 5.118

7.  The role of eosinophils in immunotherapy.

Authors: 
Journal:  Curr Opin Allergy Clin Immunol       Date:  2020-04
  7 in total

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