R E Kohler1, A Moses2, R Krysiak1, N G Liomba2, S Gopal2. 1. Department of Health Policy and Management University of Chapel Hill at North Carolina. 2. University of North Carolina Project Malawi.
Abstract
BACKGROUND: Breast cancer is the most common female cancer in Africa, yet no published studies have investigated breast cancer in Malawi. Understanding the clinical profile of breast cancer is important to develop early diagnosis efforts. AIM: To describe clinical and pathological characteristics of breast specimens from a pathology laboratory at a national teaching hospital. METHODS: Secondary analysis of pathology reports from July 2011 to September 2013. RESULTS: Among 85 breast cancer cases, 55% were < 50 years. Median tumor size was 4 cm and 49% were grade 3. Median symptom duration was eight months. CONCLUSIONS: Malawian women with breast cancer commonly have long symptom durations prior to diagnosis, young age, and poorly differentiated tumors. Improved clinical and pathological characterization, including hormone receptor status, are urgently needed to better understand this disease in Malawi.
BACKGROUND:Breast cancer is the most common female cancer in Africa, yet no published studies have investigated breast cancer in Malawi. Understanding the clinical profile of breast cancer is important to develop early diagnosis efforts. AIM: To describe clinical and pathological characteristics of breast specimens from a pathology laboratory at a national teaching hospital. METHODS: Secondary analysis of pathology reports from July 2011 to September 2013. RESULTS: Among 85 breast cancer cases, 55% were < 50 years. Median tumor size was 4 cm and 49% were grade 3. Median symptom duration was eight months. CONCLUSIONS: Malawian women with breast cancer commonly have long symptom durations prior to diagnosis, young age, and poorly differentiated tumors. Improved clinical and pathological characterization, including hormone receptor status, are urgently needed to better understand this disease in Malawi.
Authors: C A Adisa; N Eleweke; Au A Alfred; M J Campbell; R Sharma; O Nseyo; V Tandon; R Mukhtar; A Greninger; J Di Risi; L J Esserman Journal: Ann Afr Med Date: 2012 Jul-Sep
Authors: Ahmedin Jemal; Freddie Bray; Melissa M Center; Jacques Ferlay; Elizabeth Ward; David Forman Journal: CA Cancer J Clin Date: 2011-02-04 Impact factor: 508.702
Authors: Adekunle Adesina; David Chumba; Ann M Nelson; Jackson Orem; Drucilla J Roberts; Henry Wabinga; Michael Wilson; Timothy R Rebbeck Journal: Lancet Oncol Date: 2013-04 Impact factor: 41.316
Authors: Satish Gopal; Robert Krysiak; N George Liomba; Marie-Josephe Horner; Carol G Shores; Noor Alide; Steve Kamiza; Coxcilly Kampani; Fred Chimzimu; Yuri Fedoriw; Dirk P Dittmer; Mina C Hosseinipour; Irving F Hoffman Journal: PLoS One Date: 2013-08-07 Impact factor: 3.240
Authors: Valerie A McCormack; Maureen Joffe; Eunice van den Berg; Nadine Broeze; Isabel dos Santos Silva; Isabelle Romieu; Judith S Jacobson; Alfred I Neugut; Joachim Schüz; Herbert Cubasch Journal: Breast Cancer Res Date: 2013 Impact factor: 6.466
Authors: Racquel E Kohler; Satish Gopal; Anna R Miller; Clara N Lee; Bryce B Reeve; Bryan J Weiner; Stephanie B Wheeler Journal: Patient Educ Couns Date: 2016-08-09
Authors: Hari S Iyer; Racquel E Kohler; Doreen Ramogola-Masire; Carolyn Brown; Kesaobaka Molebatsi; Surbhi Grover; Irene Kablay; Memory Bvochora-Nsingo; Jason A Efstathiou; Shahin Lockman; Neo Tapela; Scott L Dryden-Peterson Journal: PLoS One Date: 2019-06-06 Impact factor: 3.752
Authors: Vincent DeGennaro; Faiz Jiwani; Elizabeth Patberg; Martin Gibbs; Rachel Libby; Dieudina Gabriel; Coy D Heldermon; Karen Daily; Joseph Bernard Journal: J Glob Oncol Date: 2018-09