Literature DB >> 26133230

Total Synthesis of Shishijimicin A.

K C Nicolaou1, Zhaoyong Lu1, Ruofan Li1, James R Woods1, Te-ik Sohn1.   

Abstract

The total synthesis of the rare but extremely potent antitumor agent shishijimicin A has been achieved via a convergent strategy involving carboline disaccharide 3 and hydroxy enediyne thioacetate 4.

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Year:  2015        PMID: 26133230     DOI: 10.1021/jacs.5b05575

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  5 in total

1.  Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine.

Authors:  K C Nicolaou; Stephan Rigol
Journal:  Nat Prod Rep       Date:  2020-04-22       Impact factor: 13.423

2.  Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234.

Authors:  Ling Liu; Jian Pan; Zilong Wang; Xiaohui Yan; Dong Yang; Xiangcheng Zhu; Ben Shen; Yanwen Duan; Yong Huang
Journal:  J Ind Microbiol Biotechnol       Date:  2018-02-02       Impact factor: 3.346

3.  Enantioselective Total Synthesis of (+)-EBC-23, a Potent Anticancer Agent from the Australian Rainforest.

Authors:  Arun K Ghosh; Che-Sheng Hsu
Journal:  J Org Chem       Date:  2021-04-19       Impact factor: 4.354

Review 4.  Recent Advances in the Synthesis of β-Carboline Alkaloids.

Authors:  Tímea Szabó; Balázs Volk; Mátyás Milen
Journal:  Molecules       Date:  2021-01-27       Impact factor: 4.411

Review 5.  Antibody-Drug Conjugates Containing Payloads from Marine Origin.

Authors:  Iván Cheng-Sánchez; Federico Moya-Utrera; Cristina Porras-Alcalá; Juan M López-Romero; Francisco Sarabia
Journal:  Mar Drugs       Date:  2022-07-30       Impact factor: 6.085

  5 in total

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