Literature DB >> 26132717

Influence of Partner Type on Acceptability and Likelihood of Use of a Rectal Microbicide Among Young Men Who Have Sex With Men in the United States and Puerto Rico.

Rebecca Giguere1, Curtis Dolezal1, José A Bauermeister2, Timothy Frasca1, Juan Valladares1, Irma Febo3, Ross D Cranston4, Kenneth Mayer5, Ian McGowan6, Alex Carballo-Diéguez1.   

Abstract

This study examined how acceptability of placebo gel with receptive anal intercourse (RAI) and likelihood of future rectal microbicide use varied across partner types. Because no rectal microbicide is available yet, use of placebo permitted the study of gel use behavior in real-life circumstances. A total of 87 men who have sex with men (MSM) aged 18 to 30 years inserted placebo gel rectally before RAI during 12 weeks. Using mixed-methods design, participants completed a behavioral questionnaire and in-depth interview. In all, 62 men (71.3%) reported gel use with a lover (i.e., spouse equivalent, boyfriend), 32 (36.8%) with a one-night stand (i.e., man with whom you had sex once), and 29 (33.3%) with an "other" male partner. While gel acceptability was high across partner types, use with lovers was facilitated by trust and familiarity; yet trust made participants believe protection was less necessary. Conversely, participants expressed high likelihood of using gel with one-night stands, whom they perceived as riskier; yet they felt less comfortable discussing gel with them, often resorting to covert use or forgoing gel. A successful microbicide will be positioned as a sexual pleasure enhancer so that men can present it to their lovers and other partners as a gel that improves sex and secondarily prevents human immunodeficiency virus (HIV).

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Year:  2015        PMID: 26132717      PMCID: PMC4698091          DOI: 10.1080/00224499.2014.1002127

Source DB:  PubMed          Journal:  J Sex Res        ISSN: 0022-4499


  20 in total

1.  Relationship characteristics and sexual risk-taking in young men who have sex with men.

Authors:  Brian Mustanski; Michael E Newcomb; Elise M Clerkin
Journal:  Health Psychol       Date:  2011-09       Impact factor: 4.267

2.  The fallacy of intimacy: sexual risk behaviour and beliefs about trust and condom use among men who have sex with men in South Africa.

Authors:  Justin Knox; Huso Yi; Vasu Reddy; Senkhu Maimane; Theo Sandfort
Journal:  Psychol Health Med       Date:  2010-12       Impact factor: 2.423

3.  Variations in patterns of sexual risk behavior among Seattle-area MSM based on their HIV status, the HIV status of their partner and partner type.

Authors:  Richard D Burt; Hanne Thiede
Journal:  AIDS Behav       Date:  2012-04

4.  Rectal microbicides: can we make them and will people use them?

Authors:  Ian McGowan
Journal:  AIDS Behav       Date:  2011-04

5.  HIV risk behaviors and obstacles to condom use among Puerto Rican men in New York City who have sex with men.

Authors:  A Carballo-Diéguez; C Dolezal
Journal:  Am J Public Health       Date:  1996-11       Impact factor: 9.308

6.  Achieving Safety: Safer Sex, Communication, and Desire among Young Gay Men.

Authors:  Anna Eisenberg; José Bauermeister; Michelle Marie Johns; Emily Pingel; Matthew Leslie Santana
Journal:  J Adolesc Res       Date:  2011-09-01

7.  Willingness to use microbicides varies by race/ethnicity, experience with prevention products, and partner type.

Authors:  Kathleen M Morrow; Joseph L Fava; Rochelle K Rosen; Anna L Christensen; Sara Vargas; Candelaria Barroso
Journal:  Health Psychol       Date:  2007-11       Impact factor: 4.267

8.  Behavioral and cognitive barriers to safer sex between men in steady relationships: implications for prevention strategies.

Authors:  Udi Davidovich; John B F de Wit; Wolfgang Stroebe
Journal:  AIDS Educ Prev       Date:  2004-08

9.  Acceptability of UC781 gel as a rectal microbicide among HIV-uninfected women and men.

Authors:  Ana Ventuneac; Alex Carballo-Diéguez; Ian McGowan; Robert Dennis; Amy Adler; Elena Khanukhova; Charles Price; Terry Saunders; Chomchay Siboliban; Peter Anton
Journal:  AIDS Behav       Date:  2009-09-11

Review 10.  How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis and treatment as prevention.

Authors:  Ingrid Young; Lisa McDaid
Journal:  AIDS Behav       Date:  2014-02
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  9 in total

1.  Patterns of a Rectal Microbicide Placebo Gel Use in a Preparatory Stage for a Phase I Trial Among Young Men Who Have Sex with Men.

Authors:  José A Bauermeister; R Giguere; C S Leu; C Dolezal; I Febo; R D Cranston; K Mayer; I McGowan; A Carballo-Diéguez
Journal:  AIDS Behav       Date:  2018-02

2.  Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use.

Authors:  Kate M Guthrie; Rochelle K Rosen; Melissa Guillen; Jaime J Ramirez; Sara E Vargas; Joseph L Fava; Anthony S Ham; David F Katz; Susan Cu-Uvin; Sheila Tumilty; Kelley A Smith; Karen W Buckheit; Robert W Buckheit
Journal:  AIDS Res Hum Retroviruses       Date:  2021-10-18       Impact factor: 1.723

3.  Acceptability of a Dapivirine Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-033 Study).

Authors:  José A Bauermeister; Ryan C Tingler; Sherri Johnson; Nicole Macagna; Jonathan Lucas; Clara Dominguez-Islas; Daniel Szydlo; Julie Ngo; Cindy E Jacobson; Lindsay Kramzer; Devika Singh; Charlene S Dezzutti; Ratiya Pamela Kunjara Na Ayudhya; Jeanna Piper; Bríd Devlin; Craig W Hendrix; Ken Ho
Journal:  AIDS Educ Prev       Date:  2021-10

4.  Acceptability of a Dapivirine/Placebo Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-026).

Authors:  José A Bauermeister; Ryan C Tingler; Clara Dominguez; Eileen F Dunne; Craig Hoesley; Ken Ho; Sherri Johnson; Jonathan Lucas; Nicole Macagna; Elizabeth Brown; Holly Gundacker; Melissa Peda; Cindy E Jacobson; Lindsay Kramzer; Devika Singh; Charlene S Dezzutti; Ratiya Pamela Kunjara Na Ayudhya; Mark A Marzinke; Jeanna Piper; Bríd Devlin; Jeremy Nuttall; Ian McGowan; Craig W Hendrix; Ross D Cranston
Journal:  AIDS Behav       Date:  2021-10-17

5.  Antiretroviral pre-exposure prophylaxis preferences among men who have sex with men in Vietnam: results from a nationwide cross-sectional survey.

Authors:  Catherine E Oldenburg; Bao Le; Hoang Thi Huyen; Dinh Duc Thien; Nguyen Hoang Quan; Katie B Biello; Amy Nunn; Philip A Chan; Kenneth H Mayer; Matthew J Mimiaga; Donn Colby
Journal:  Sex Health       Date:  2016-07-22       Impact factor: 2.706

6.  Preference of Oral Tenofovir Disoproxil Fumarate/Emtricitabine Versus Rectal Tenofovir Reduced-Glycerin 1% Gel Regimens for HIV Prevention Among Cisgender Men and Transgender Women Who Engage in Receptive Anal Intercourse with Men.

Authors:  Alex Carballo-Diéguez; Rebecca Giguere; Curtis Dolezal; Cheng-Shiun Leu; Iván C Balán; William Brown; Christine Rael; Barbra A Richardson; Jeanna M Piper; Linda-Gail Bekker; Suwat Chariyalertsak; Anupong Chitwarakorn; Pedro Gonzales; Timothy H Holtz; Albert Liu; Kenneth H Mayer; Carmen D Zorrilla; Javier R Lama; Ian McGowan; Ross D Cranston
Journal:  AIDS Behav       Date:  2017-12

7.  Hypothetical Rectal Microbicide Acceptability and Factors Influencing It among Men Who Have Sex with Men in Tianjin, China.

Authors:  Guohong Zhang; Huifang Zhang; Hongxuyang Yu; Zheng Zhao; Jie Yang; Mianzhi Zhang; Minying Zhang
Journal:  PLoS One       Date:  2016-05-31       Impact factor: 3.240

8.  Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women.

Authors:  Ian McGowan; Ross D Cranston; Kenneth H Mayer; Irma Febo; Kathryn Duffill; Aaron Siegel; Jarret C Engstrom; Alexyi Nikiforov; Seo-Young Park; Rhonda M Brand; Cindy Jacobson; Rebecca Giguere; Curtis Dolezal; Timothy Frasca; Cheng-Shiun Leu; Jill L Schwartz; Alex Carballo-Diéguez
Journal:  PLoS One       Date:  2016-06-30       Impact factor: 3.240

9.  Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression.

Authors:  Laura Romas; Kenzie Birse; Kenneth H Mayer; Max Abou; Garrett Westmacott; Rebecca Giguere; Irma Febo; Ross D Cranston; Alex Carballo-Diéguez; Ian McGowan; Adam Burgener
Journal:  AIDS Res Hum Retroviruses       Date:  2016-08-02       Impact factor: 2.205

  9 in total

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