Literature DB >> 26131405

Changing organ allocation policy for kidney transplantation in the United States.

Bhavna Chopra1, Kalathil K Sureshkumar1.   

Abstract

The new kidney allocation scheme (KAS) in effect since December 4(th) 2014 was designed to overcome the shortcomings of previous system. A key feature of the new KAS is preferential allocation of best quality organs to wait-list candidates with the longest predictive survival in a concept called longevity matching. Highly sensitized recipients would get extra points and enjoy widespread sharing of organs in order to increase accessibility to transplant. Wait-list candidates with blood group B will be offered organs from donors with A2 and A2B blood type in order to shorten their wait-list time. Time on the wait list will start from day of listing or date of initiation of dialysis whichever comes first which should benefit candidates with limited resources who might be late to get on the transplant list. Pay back system has been eliminated in the new KAS. These changes in organ allocation policy may lead to increase in median half-life of the allograft and increase the number of transplants; thus resulting in better utilization of a scarce resource. There could be unintended negative consequences which may become evident over time.

Keywords:  Expected post-transplant survival; Highly sensitized; Kidney donor profile index; Longevity matching; New kidney allocation scheme

Year:  2015        PMID: 26131405      PMCID: PMC4478598          DOI: 10.5500/wjt.v5.i2.38

Source DB:  PubMed          Journal:  World J Transplant        ISSN: 2220-3230


  18 in total

1.  The kidney allocation system.

Authors:  John J Friedewald; Ciara J Samana; Bertram L Kasiske; Ajay K Israni; Darren Stewart; Wida Cherikh; Richard N Formica
Journal:  Surg Clin North Am       Date:  2013-12       Impact factor: 2.741

2.  The new OPTN kidney allocation policy: potential for inequitable access among highly sensitized patients.

Authors:  R A Bray; P Brannon; C Breitenbach; C Bryan; D-F Chen; J Lai; T McRacken; A Kirk; B Kaplan; T Pearson; H M Gebel
Journal:  Am J Transplant       Date:  2014-11-17       Impact factor: 8.086

3.  Simulating the new kidney allocation policy in the United States: modest gains and many unknowns.

Authors:  Jesse D Schold; Peter P Reese
Journal:  J Am Soc Nephrol       Date:  2014-05-15       Impact factor: 10.121

4.  The new kidney allocation system (KAS) and the highly sensitized patient: expect the unexpected.

Authors:  R A Bray; H M Gebel
Journal:  Am J Transplant       Date:  2014-10-01       Impact factor: 8.086

5.  OPTN/SRTR 2011 Annual Data Report: kidney.

Authors:  A J Matas; J M Smith; M A Skeans; K E Lamb; S K Gustafson; C J Samana; D E Stewart; J J Snyder; A K Israni; B L Kasiske
Journal:  Am J Transplant       Date:  2013-01       Impact factor: 8.086

6.  Effect of dialysis initiation for preemptively listed candidates in the revised kidney allocation policy.

Authors:  J D Schold; L D Buccini; P P Reese; E D Poggio; D A Goldfarb
Journal:  Am J Transplant       Date:  2014-10-02       Impact factor: 8.086

7.  Preemptive kidney transplantation: the advantage and the advantaged.

Authors:  Bertram L Kasiske; Jon J Snyder; Arthur J Matas; Mary D Ellison; John S Gill; Annamaria T Kausz
Journal:  J Am Soc Nephrol       Date:  2002-05       Impact factor: 10.121

8.  A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index.

Authors:  Panduranga S Rao; Douglas E Schaubel; Mary K Guidinger; Kenneth A Andreoni; Robert A Wolfe; Robert M Merion; Friedrich K Port; Randall S Sung
Journal:  Transplantation       Date:  2009-07-27       Impact factor: 4.939

9.  Race and socioeconomic factors influencing early placement on the kidney transplant waiting list.

Authors:  B L Kasiske; W London; M D Ellison
Journal:  J Am Soc Nephrol       Date:  1998-11       Impact factor: 10.121

10.  New national allocation policy for deceased donor kidneys in the United States and possible effect on patient outcomes.

Authors:  Ajay K Israni; Nicholas Salkowski; Sally Gustafson; Jon J Snyder; John J Friedewald; Richard N Formica; Xinyue Wang; Eugene Shteyn; Wida Cherikh; Darren Stewart; Ciara J Samana; Adrine Chung; Allyson Hart; Bertram L Kasiske
Journal:  J Am Soc Nephrol       Date:  2014-05-15       Impact factor: 10.121

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  7 in total

1.  New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4-5 CKD.

Authors:  William S Asch; Margaret J Bia
Journal:  Clin J Am Soc Nephrol       Date:  2016-12-27       Impact factor: 8.237

Review 2.  Selection of Patients for Initial Clinical Trials of Solid Organ Xenotransplantation.

Authors:  David K C Cooper; Martin Wijkstrom; Sundaram Hariharan; Joshua L Chan; Avneesh Singh; Keith Horvath; Muhammad Mohiuddin; Arielle Cimeno; Rolf N Barth; John C LaMattina; Richard N Pierson
Journal:  Transplantation       Date:  2017-07       Impact factor: 4.939

3.  Evolving Trends in Racial Disparities for Peri-Operative Outcomes with the New Kidney Allocation System (KAS) Implementation.

Authors:  Daisy Sanchez; Derek Dubay; Baliga Prabhakar; David J Taber
Journal:  J Racial Ethn Health Disparities       Date:  2018-03-19

Review 4.  Advances in liver transplantation allocation systems.

Authors:  Michael L Schilsky; Maryam Moini
Journal:  World J Gastroenterol       Date:  2016-03-14       Impact factor: 5.742

Review 5.  Emerging approaches and technologies in transplantation: the potential game changers.

Authors:  Anil Dangi; Shuangjin Yu; Xunrong Luo
Journal:  Cell Mol Immunol       Date:  2019-02-13       Impact factor: 11.530

6.  Kidney transplantation in older recipients: Preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage.

Authors:  Bhavna Chopra; Kalathil K Sureshkumar
Journal:  World J Transplant       Date:  2018-08-09

7.  Life-Years & Rationing in the Covid-19 Pandemic: A Critical Analysis.

Authors:  MaryKatherine Gaurke; Bernard Prusak; Kyeong Yun Jeong; Emily Scire; Daniel P Sulmasy
Journal:  Hastings Cent Rep       Date:  2021-09       Impact factor: 2.683

  7 in total

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