Naiqing Liu1, Zhengchuan Niu2, Wei Niu2, Cheng Peng2, Xueqing Zou2, Shuxiang Sun3, Obo Shinichi2, Muhammad Shahbaz2, Qinli Sun3, Niu Jun2. 1. Department of General Surgery, Yishui Central Hospital Linyi 276400, Shandong, P. R. China ; Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University Jinan 250012, Shandong, P. R. China. 2. Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University Jinan 250012, Shandong, P. R. China. 3. Department of General Surgery, Yishui Central Hospital Linyi 276400, Shandong, P. R. China.
Abstract
AIMS: The aim of this retrospective study is to explore the effects of sentinel lymph node (SLN) mapping guided laparoscopic-assisted distal gastrectomy (LADG) for distal gastric cancer. METHODS: Two hundred patients were enrolled in this study. One hundred and one patients undergoing SLN guided LADG were designated as the SLN group. Ninety-nine patients having conventional LADG with D1 or D2 lymph node dissection were designated as the control group. Intraoperative and postoperative indicators such as the number of lymph nodes dissected, intraoperative and postoperative conditions, flow cytometry analysis of T lymphocyte subsets and natural killer (NK) cells, survival rates, recurrence rates and postoperative complications were investigated between these two groups. RESULTS: The number of lymph nodes dissected in the SLN group was significantly lesser than that in the control group. Furthermore, in the SLN group, the patients achieved better immunization status, improved intraoperative and postoperative conditions and decreased postoperative complications. There were no significant differences were found in the positive lymph nodes detected, the distance between proximal and distal cutting edge, postoperative survival or recurrence rates. CONCLUSIONS: SLN guided LADG for gastric cancer is a safe and effective method and could achieve an equal clinical effect as traditional laparoscopic D1 or D2 radical operation with less operation trauma and better recovery.
AIMS: The aim of this retrospective study is to explore the effects of sentinel lymph node (SLN) mapping guided laparoscopic-assisted distal gastrectomy (LADG) for distal gastric cancer. METHODS: Two hundred patients were enrolled in this study. One hundred and one patients undergoing SLN guided LADG were designated as the SLN group. Ninety-nine patients having conventional LADG with D1 or D2 lymph node dissection were designated as the control group. Intraoperative and postoperative indicators such as the number of lymph nodes dissected, intraoperative and postoperative conditions, flow cytometry analysis of T lymphocyte subsets and natural killer (NK) cells, survival rates, recurrence rates and postoperative complications were investigated between these two groups. RESULTS: The number of lymph nodes dissected in the SLN group was significantly lesser than that in the control group. Furthermore, in the SLN group, the patients achieved better immunization status, improved intraoperative and postoperative conditions and decreased postoperative complications. There were no significant differences were found in the positive lymph nodes detected, the distance between proximal and distal cutting edge, postoperative survival or recurrence rates. CONCLUSIONS: SLN guided LADG for gastric cancer is a safe and effective method and could achieve an equal clinical effect as traditional laparoscopic D1 or D2 radical operation with less operation trauma and better recovery.
Authors: Bruno Märkl; Alexandra I Moldovan; Hendrik Jähnig; Claudio Cacchi; Hanno Spatz; Matthias Anthuber; Daniel V Oruzio; Hallie Kretsinger; Hans M Arnholdt Journal: Ann Surg Oncol Date: 2011-04-19 Impact factor: 5.344
Authors: P M Goh; A Z Khan; J B So; D Lomanto; W K Cheah; R Muthiah; A Gandhi Journal: Surg Laparosc Endosc Percutan Tech Date: 2001-04 Impact factor: 1.719