Sida Wang1, Chunyan Liao1, Shuyuan Liang1, Danni Zhong2, Junjie Liu1, Zhixian Li1. 1. Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China. 2. Department of Neonatology, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
Abstract
OBJECTIVE: To investigate the ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage (PIVH) after different treatments, and to evaluate the neurological outcomes of mild PIVH with Gesell Development Diagnosis Scale (GDDS). METHODS: A total of 194 newborns with grade I-II PIVH were recruited, and findings of cranial ultrasound examination before and 1 month after birth were included for analysis. The echo intensity and size of the lesions were recorded. RESULTS: There was no significant difference in the echo intensity among three groups of grade I PIVH patients (P>0.05). There was significant difference in the echo intensity among three groups of grade II PIVH patients, and the ganglioside had the best therapeutic efficacy (P<0.05). No significant difference was observed in the area change among three groups of grade I PIVH patients (P>0.05). However, significant difference was observed in the area change among three groups of grade II PIVH patients, and ganglioside had a better efficacy than cerebrolysin and control agent (P<0.05), but there was no significant difference between cerebrolysin and control groups (P>0.05). GDDS evaluation showed no significant difference among three groups (P>0.05), and all the patients recovered completely. CONCLUSION: The efficacy of different treatments for mild PIVH can be reflected in the ultrasound findings. Mild PIVH children generally have a good neurological prognosis.
OBJECTIVE: To investigate the ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage (PIVH) after different treatments, and to evaluate the neurological outcomes of mild PIVH with Gesell Development Diagnosis Scale (GDDS). METHODS: A total of 194 newborns with grade I-II PIVH were recruited, and findings of cranial ultrasound examination before and 1 month after birth were included for analysis. The echo intensity and size of the lesions were recorded. RESULTS: There was no significant difference in the echo intensity among three groups of grade I PIVH patients (P>0.05). There was significant difference in the echo intensity among three groups of grade II PIVH patients, and the ganglioside had the best therapeutic efficacy (P<0.05). No significant difference was observed in the area change among three groups of grade I PIVH patients (P>0.05). However, significant difference was observed in the area change among three groups of grade II PIVH patients, and ganglioside had a better efficacy than cerebrolysin and control agent (P<0.05), but there was no significant difference between cerebrolysin and control groups (P>0.05). GDDS evaluation showed no significant difference among three groups (P>0.05), and all the patients recovered completely. CONCLUSION: The efficacy of different treatments for mild PIVH can be reflected in the ultrasound findings. Mild PIVH children generally have a good neurological prognosis.
Entities:
Keywords:
Gesell Development Diagnosis Scale; Periventricular-intraventricular hemorrhage; neonatal; ultrasound
Authors: Emily W Y Tam; Glenn Rosenbluth; Elizabeth E Rogers; Donna M Ferriero; David Glidden; Ruth B Goldstein; Hannah C Glass; Robert E Piecuch; A James Barkovich Journal: J Pediatr Date: 2010-09-15 Impact factor: 4.406
Authors: Karl Kuban; Ira Adler; Elizabeth N Allred; Daniel Batton; Steven Bezinque; Bradford W Betz; Ellen Cavenagh; Sara Durfee; Kirsten Ecklund; Kate Feinstein; Lynn Ansley Fordham; Frederick Hampf; Joseph Junewick; Robert Lorenzo; Roy McCauley; Cindy Miller; Joanna Seibert; Barbara Specter; Jacqueline Wellman; Sjirk Westra; Alan Leviton Journal: Pediatr Radiol Date: 2007-09-28