| Literature DB >> 26126749 |
J Mick Tilford1,2, Nalin Payakachat3, Karen A Kuhlthau4,5, Jeffrey M Pyne6, Erica Kovacs7, Jayne Bellando8, D Keith Williams9, Werner B F Brouwer10, Richard E Frye8.
Abstract
Sleep problems in children with autism spectrum disorders (ASD) are under-recognized and under-treated. Identifying treatment value accounting for health effects on family members (spillovers) could improve the perceived cost-effectiveness of interventions to improve child sleep habits. A prospective cohort study (N = 224) was conducted with registry and postal survey data completed by the primary caregiver. We calculated quality of life outcomes for the child and the primary caregiver associated with treatments to improve sleep in the child based on prior clinical trials. Predicted treatment effects for melatonin and behavioral interventions were similar in magnitude for the child and for the caregiver. Accounting for caregiver spillover effects associated with treatments for the child with ASD increases treatment benefits and improves cost-effectiveness profiles.Entities:
Keywords: Autism spectrum disorder; Caregiver health; Child health; Child sleep habits; Cost-effectiveness analysis; Quality adjusted life year
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Year: 2015 PMID： 26126749 PMCID： PMC4609586 DOI： 10.1007/s10803-015-2507-5
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257