| Literature DB >> 2612607 |
Abstract
Penicillin-induced paroxysmal depolarization shifts (PDS) are followed by prolonged afterhyperpolarizations of about 2 seconds duration. Intracellular injection of EGTA blocked a late component of the afterhyperpolarizations; an early one lasting up to one second was only slightly reduced by EGTA. It is concluded that afterhyperpolarizations following penicillin-induced PDS comprise different components: an initial one lasting up to one second which is not Ca2+-dependent and a slow one lasting up to two seconds which is caused by a Ca2+-dependent K+ current.Entities:
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Year: 1989 PMID: 2612607 DOI: 10.1007/bf00230253
Source DB: PubMed Journal: Exp Brain Res ISSN: 0014-4819 Impact factor: 1.972