Literature DB >> 2612607

Calcium-dependent potassium current following penicillin-induced epileptiform discharges in the hippocampal slice.

R Domann1, T Dorn, O W Witte.   

Abstract

Penicillin-induced paroxysmal depolarization shifts (PDS) are followed by prolonged afterhyperpolarizations of about 2 seconds duration. Intracellular injection of EGTA blocked a late component of the afterhyperpolarizations; an early one lasting up to one second was only slightly reduced by EGTA. It is concluded that afterhyperpolarizations following penicillin-induced PDS comprise different components: an initial one lasting up to one second which is not Ca2+-dependent and a slow one lasting up to two seconds which is caused by a Ca2+-dependent K+ current.

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Year:  1989        PMID: 2612607     DOI: 10.1007/bf00230253

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN: 0014-4819            Impact factor:   1.972


  8 in total

1.  Separation of different types of afterpotentials following penicillin-induced paroxysmal depolarization shifts of neurons in the motor cortex of the rat.

Authors:  O W Witte; S Uhlig; E Valle
Journal:  Neurosci Lett       Date:  1989-06-05       Impact factor: 3.046

2.  Effects of EGTA on the calcium-activated afterhyperpolarization in hippocampal CA3 pyramidal cells.

Authors:  P A Schwartzkroin; C E Stafstrom
Journal:  Science       Date:  1980-12-05       Impact factor: 47.728

3.  Participation of calcium spikes during intrinsic burst firing in hippocampal neurons.

Authors:  R K Wong; D A Prince
Journal:  Brain Res       Date:  1978-12-29       Impact factor: 3.252

4.  Epileptiform burst afterhyperolarization: calcium-dependent potassium potential in hippocampal CA1 pyramidal cells.

Authors:  B E Alger; R A Nicoll
Journal:  Science       Date:  1980-12-05       Impact factor: 47.728

5.  A bicuculline-resistant inhibitory post-synaptic potential in rat hippocampal pyramidal cells in vitro.

Authors:  N R Newberry; R A Nicoll
Journal:  J Physiol       Date:  1984-03       Impact factor: 5.182

6.  Hyperpolarizing potentials in guinea pig hippocampal CA3 neurons.

Authors:  W D Knowles; J H Schneiderman; H V Wheal; C E Stafstrom; P A Schwartzkroin
Journal:  Cell Mol Neurobiol       Date:  1984-09       Impact factor: 5.046

7.  Effects of intracellular injections of chloride and EGTA on postepileptiform-burst hyperpolarizations in hippocampal neurons.

Authors:  J J Hablitz
Journal:  Neurosci Lett       Date:  1981-03-10       Impact factor: 3.046

8.  Motor cortical epileptic foci in vivo: actions of a calcium channel blocker on paroxysmal neuronal depolarizations.

Authors:  O W Witte; E J Speckmann; J Walden
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1987-01
  8 in total
  4 in total

1.  Participation of interneurons in penicillin-induced epileptic discharges.

Authors:  R Domann; S Uhlig; T Dorn; O W Witte
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

2.  Antibiotic supplements affect electrophysiological properties and excitability of rat hippocampal pyramidal neurons in primary culture.

Authors:  Farideh Bahrami; Mahyar Janahmadi
Journal:  Iran Biomed J       Date:  2013-04

3.  Afterpotentials following penicillin-induced paroxysmal depolarizations in rat hippocampal CA1 pyramidal cells in vitro.

Authors:  R Domann; T Dorn; O W Witte
Journal:  Pflugers Arch       Date:  1991-01       Impact factor: 3.657

4.  Inhibitory mechanisms in epileptiform activity induced by low magnesium.

Authors:  C H Westerhoff; R Domann; O W Witte
Journal:  Pflugers Arch       Date:  1995-06       Impact factor: 3.657

  4 in total

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