J H Yang1, S W Suh1, Y-S Park2, J-H Lee3, B K Park4, C H Ham1, J W Choi1. 1. Department of Orthopedics, Scoliosis Research Institute, Korea University Medical College, Guro Hospital, Seoul, Korea. 2. Department of Orthopedics, Hanyang University, Guri Hospital, Guri, Korea. 3. Department of Orthopedics, Kyung-hee University Medical Center, Seoul, Korea. 4. Department of Physical Medicine and Rehabilitation, Korea University Medical College, Ansan Hospital, Ansan-si, Korea.
Abstract
STUDY DESIGN: Experimental study. OBJECTIVES: To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model. SETTING: Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea. METHODS: Rabbits (n =18) were divided into Complete (n = 9) and Incomplete (n = 9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (⩾ 80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated. RESULTS: Experimental conditions between the two groups were statistically similar (P > 0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P > 0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7 ± 0.5°C in comparison to 0.5 ± 0.1°C in the Incomplete SCI Group (P < 0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P < 0.001), while white and gray matter damage was variable on histology. CONCLUSIONS: Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.
STUDY DESIGN: Experimental study. OBJECTIVES: To study the role of surface temperature as an adjunct to motor evoked potentials (MEPs) in rabbit spinal cord injury (SCI) model. SETTING: Department of Orthopedics, Korea University Guro Hospital, Seoul, Korea. METHODS:Rabbits (n =18) were divided into Complete (n = 9) and Incomplete (n = 9) SCI groups. Complete SCI was defined as being non-responsive to a wake-up test with loss of MEPs after transection of spinal cord. Incomplete SCI was defined as being responsive to a wake-up test with significant attenuation (⩾ 80%) of MEPs after impaction on spinal cord. Surface temperature of upper and lower extremities, core temperature and MEPs signals were checked before, during and after SCI for 20 min. A wake-up test was conducted and spinal cord was histologicaly evaluated. RESULTS: Experimental conditions between the two groups were statistically similar (P > 0.005 for all values). After SCI, upper extremity temperatures did not change in either group (P > 0.005); however, the surface temperature of the lower extremities in the Complete SCI Group elevated to 1.7 ± 0.5°C in comparison to 0.5 ± 0.1°C in the Incomplete SCI Group (P < 0.001). The scores of wake-up test in the Incomplete SCI Group were significantly different from that of the Complete SCI Group (P < 0.001), while white and gray matter damage was variable on histology. CONCLUSIONS: Monitoring of changes of body surface temperature of the lower extremities can be potentially used to identify the completeness of SCI in a rabbit model.
Authors: T Brett Reece; Jonathan D Davis; David O Okonkwo; Thomas S Maxey; Peter I Ellman; Xinning Li; Joel Linden; Curtis G Tribble; Irving L Kron; John A Kern Journal: J Surg Res Date: 2004-09 Impact factor: 2.192
Authors: Constantin Popa; Florian Popa; Valentin Titus Grigorean; Gelu Onose; Aurelia Mihaela Sandu; Mihai Popescu; Gheorghe Burnei; Victor Strambu; Crina Sinescu Journal: J Med Life Date: 2010 Jul-Sep