| Literature DB >> 26122111 |
Lucian C Warth1, Andrew J Pugely1, Christopher T Martin1, Yubo Gao1, John J Callaghan1.
Abstract
26-27% of patients with end stage hip and knee arthritis requiring TJR have chronic renal disease. A multi-center, prospective clinical registry was queried for TJA's from 2006 to 2012, and 74,300 cases were analyzed. Renal impairment was quantified using estimated glomerular filtration rate (eGFR) to stratify each patient by stage of CRD (1-5). There was a significantly greater rate of overall complications in patients with moderate to severe CRD (6.1% vs. 7.6%, P<0.001). In those with CRD (Stage 3-5), mortality was twice as high (0.26% vs. 0.48%, P<0.001). Patients with Stage 4 and 5 CRD had a 213% increased risk of any complication (OR 2.13, 95% CI: 1.73-2.62). Surgeons may use these findings to discuss the risk-benefit ratio of elective TJR in patients with CRD.Entities:
Keywords: ACS NSQIP; chronic renal disease; database; eGFR (estimated glomerular filtration rate); total joint arthroplasty
Mesh：
Year: 2015 PMID： 26122111 DOI： 10.1016/j.arth.2014.12.037
Source DB: PubMed Journal: J Arthroplasty ISSN： 0883-5403 Impact factor: 4.757