Literature DB >> 26097122

Targeted Therapy for Breast Cancer Stem Cells by Liposomal Delivery of siRNA against Fibronectin EDB.

Yujin Sun1,2, Hoe Suk Kim1, Phei Er Saw3, Sangyong Jon3, Woo Kyung Moon1.   

Abstract

Targeted therapy for breast cancer stem cell (BCSC): A novel liposomal system (APTEDB -LS-siRNA(EDB) ) that enables simultaneous targeting and knockdown of extra domain B of fibronectin (EDB-FN) shows potent therapeutic efficacy in the BCSC-derived tumors in vivo.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  RNA; aptides; breast cancer; fibronectin; liposomes; stem cells; targeted cancer therapy

Mesh：

Substances：

Year:  2015        PMID： 26097122     DOI： 10.1002/adhm.201500190

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  5 in total

1.  Theranostics for Breast Cancer Stem Cells.

Authors:  Woo Kyung Moon; Hoe Suk Kim
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Targeting Fibronectin for Cancer Imaging and Therapy.

Authors:  Zheng Han; Zheng-Rong Lu
Journal:  J Mater Chem B       Date:  2016-12-01       Impact factor: 6.331

Review 3.  Cancer stem cells and strategies for targeted drug delivery.

Authors:  Jin Cao; Shubhmita Bhatnagar; Jiawei Wang; Xueyong Qi; Swayam Prabha; Jayanth Panyam
Journal:  Drug Deliv Transl Res       Date:  2020-10-23       Impact factor: 5.671

4.  Overexpression of Extradomain-B Fibronectin is Associated with Invasion of Breast Cancer Cells.

Authors:  Amita Vaidya; Helen Wang; Victoria Qian; Hannah Gilmore; Zheng-Rong Lu
Journal:  Cells       Date:  2020-08-03       Impact factor: 6.600

5.  Noninvasive assessment and therapeutic monitoring of drug-resistant colorectal cancer by MR molecular imaging of extradomain-B fibronectin.

Authors:  Amita Vaidya; Nadia Ayat; Megan Buford; Helen Wang; Aman Shankardass; Yiqing Zhao; Hannah Gilmore; Zhenghe Wang; Zheng-Rong Lu
Journal:  Theranostics       Date:  2020-09-08       Impact factor: 11.556
  5 in total

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