Literature DB >> 26096645

Combined chemotherapy and photodynamic therapy using a nanohybrid based on layered double hydroxides to conquer cisplatin resistance.

Zhigang Wang1, Rong Ma, Li Yan, Xianfeng Chen, Guangyu Zhu.   

Abstract

A nanohybrid is assembled by ratiometrically co-loading Pt(IV) prodrugs and photosensitizers into layered double hydroxide nanoparticles. The nanohybrid shows synergistic cell-killing effects and is significantly active against the proliferation of cisplatin-resistant human cancer cells with nanomolar IC50 values. Profound mechanistic investigations confirm its action mode of combined chemo- and photodynamic therapy.

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Year:  2015        PMID： 26096645     DOI： 10.1039/c5cc04376j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  A fluorometric displacement assay for adenosine triphosphate using layered cobalt(II) double hydroxide nanosheets.

Authors:  Jingjing Liu; Xiao Xu; Zhitao Chen; Renfu Li; Longtian Kang; Jiannian Yao
Journal:  Mikrochim Acta       Date:  2019-03-30       Impact factor: 5.833

2.  A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells.

Authors:  Huanhuan Fan; Guobei Yan; Zilong Zhao; Xiaoxiao Hu; Wenhan Zhang; Hui Liu; Xiaoyi Fu; Ting Fu; Xiao-Bing Zhang; Weihong Tan
Journal:  Angew Chem Int Ed Engl       Date:  2016-03-24       Impact factor: 15.336

3.  Hyaluronic Acid Grafted Nanoparticles of a Platinum(II)-Silicon(IV) Phthalocyanine Conjugate for Tumor and Mitochondria-Targeted Photodynamic Therapy in Red Light.

Authors:  Koushambi Mitra; Montserrat Samso; Charles E Lyons; Matthew C T Hartman
Journal:  J Mater Chem B       Date:  2018-10-24       Impact factor: 6.331

4.  Encapsulation of palladium porphyrin photosensitizer in layered metal oxide nanoparticles for photodynamic therapy against skin melanoma.

Authors:  Zih-An Chen; Yaswanth Kuthati; Ranjith Kumar Kankala; Yu-Chuan Chang; Chen-Lun Liu; Ching-Feng Weng; Chung-Yuan Mou; Chia-Hung Lee
Journal:  Sci Technol Adv Mater       Date:  2015-10-09       Impact factor: 8.090

5.  Effective Combined Photodynamic Therapy with Lipid Platinum Chloride Nanoparticles Therapies of Oral Squamous Carcinoma Tumor Inhibition.

Authors:  Eka-Putra Gusti-Ngurah-Putu; Leaf Huang; Yih-Chih Hsu
Journal:  J Clin Med       Date:  2019-12-02       Impact factor: 4.241

Review 6.  Synergic Antitumor Effect of Photodynamic Therapy and Chemotherapy Mediated by Nano Drug Delivery Systems.

Authors:  Mozhgan Aghajanzadeh; Mostafa Zamani; Fereshteh Rajabi Kouchi; Josh Eixenberger; Dorsa Shirini; David Estrada; Farhad Shirini
Journal:  Pharmaceutics       Date:  2022-01-29       Impact factor: 6.321

7.  A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer.

Authors:  Xinning Wang; Rongcan Sun; Jing Wang; Jing Li; Ethan Walker; Aditi Shirke; Gopolakrishnan Ramamurthy; Lingpeng Shan; Dong Luo; Lauren Carmon; James P Basilion
Journal:  Theranostics       Date:  2022-02-21       Impact factor: 11.556

8.  Synthesis and Characterization of Chitosan-Coated Near-Infrared (NIR) Layered Double Hydroxide-Indocyanine Green Nanocomposites for Potential Applications in Photodynamic Therapy.

Authors:  Pei-Ru Wei; Yaswanth Kuthati; Ranjith Kumar Kankala; Chia-Hung Lee
Journal:  Int J Mol Sci       Date:  2015-09-01       Impact factor: 5.923

9.  Tumor Microenvironment Activable Self-Assembled DNA Hybrids for pH and Redox Dual-Responsive Chemotherapy/PDT Treatment of Hepatocellular Carcinoma.

Authors:  Da Zhang; Aixian Zheng; Juan Li; Ming Wu; Zhixiong Cai; Lingjie Wu; Zuwu Wei; Huanghao Yang; Xiaolong Liu; Jingfeng Liu
Journal:  Adv Sci (Weinh)       Date:  2017-01-24       Impact factor: 16.806

Review 10.  Multifunctional hypoxia imaging nanoparticles: multifunctional tumor imaging and related guided tumor therapy.

Authors:  Jiajun Liu; Zeying Liu; Daocheng Wu
Journal:  Int J Nanomedicine       Date:  2019-01-18
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