Volkert Roeloffs1, Dirk Voit1, Jens Frahm1. 1. Biomedizinische NMR Forschungs GmbH at the Max Planck Institute for Biophysical Chemistry, Goettingen, Germany.
Abstract
PURPOSE: To develop a method for spoiling transverse magnetizations without additional gradients to minimize repetition times for radial fast low angle shot (FLASH) MRI. METHODS: Residual steady state transverse magnetizations and corresponding image artifacts were analyzed for radial gradient echo sequences with constant and randomized RF phases in comparison with a sequence with refocused frequency-encoding gradients, constant spoiler gradient, and conventional RF spoiling (gold standard). The spoiling performance was assessed for different radial trajectories using numerical simulations, phantom experiments, and in vivo MRI studies of the human brain. RESULTS: Simulations as well as phantom and in vivo measurements reveal a highly efficient spoiling capacity for randomized RF phases and radial FLASH sequences without the need for gradient rewinding and spoiler gradients. The data also demonstrate a strong dependence of the spoiling performance on the chosen radial trajectory (ie, the azimuthal angular increment between successive projections) with excellent results for an interleaved multiturn scheme. CONCLUSION: Effective spoiling of transverse magnetizations in radial FLASH MRI may be achieved by randomized RF phases without additional spoiler gradients. The technique allows for short repetition times as required for high-speed real-time MRI.
PURPOSE: To develop a method for spoiling transverse magnetizations without additional gradients to minimize repetition times for radial fast low angle shot (FLASH) MRI. METHODS: Residual steady state transverse magnetizations and corresponding image artifacts were analyzed for radial gradient echo sequences with constant and randomized RF phases in comparison with a sequence with refocused frequency-encoding gradients, constant spoiler gradient, and conventional RF spoiling (gold standard). The spoiling performance was assessed for different radial trajectories using numerical simulations, phantom experiments, and in vivo MRI studies of the human brain. RESULTS: Simulations as well as phantom and in vivo measurements reveal a highly efficient spoiling capacity for randomized RF phases and radial FLASH sequences without the need for gradient rewinding and spoiler gradients. The data also demonstrate a strong dependence of the spoiling performance on the chosen radial trajectory (ie, the azimuthal angular increment between successive projections) with excellent results for an interleaved multiturn scheme. CONCLUSION: Effective spoiling of transverse magnetizations in radial FLASH MRI may be achieved by randomized RF phases without additional spoiler gradients. The technique allows for short repetition times as required for high-speed real-time MRI.
Authors: Ye Tian; Jason Mendes; Brent Wilson; Alexander Ross; Ravi Ranjan; Edward DiBella; Ganesh Adluru Journal: Magn Reson Med Date: 2020-06-03 Impact factor: 4.668