| Literature DB >> 26093320 |
Uyanga Dashdorj1, Mark Kenneth Reyes1, Afeesh Rajan Unnithan1, Arjun Prasad Tiwari1, Batgerel Tumurbaatar2, Chan Hee Park3, Cheol Sang Kim4.
Abstract
Wound dressing is a very important factor in the process of wound healing as proper wound care can accelerate the recovery of the wound. In this study, zein nanofibrous mats with fiber diameters around 350-500 nm were prepared by electrospinning and silver (Ag) nanoparticles around 20 nm were concurrently synthesized in situ into the mats. The electrospun nanofibers were characterized by Field Emission-Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis. Cell viability and activity of fibroblasts cells in zein/Ag mats were also evaluated and results demonstrated good cytocompatibility and attachment of cells on the composite nanofibers. Also, the bactericidal activity of the fabricated mats against gram-positive Staphylococcus aureus (S. aureus) and gram-negative Escherichia coli (E. coli) was investigated via zone of inhibition test and results showed high anti-bacterial performance.Entities:
Keywords: Electrospinning; Nanofibers; Silver; Wound dressing; Zein
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Year: 2015 PMID： 26093320 DOI： 10.1016/j.ijbiomac.2015.06.026
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953