Literature DB >> 26089190

Reversibly Triggered Protein-Ligand Assemblies in Giant Vesicles.

Ruud J R W Peters1, Marlies Nijemeisland1, Jan C M van Hest2.   

Abstract

External small-molecule triggers were used to reversibly control dynamic protein-ligand interactions in giant vesicles. An alcohol dehydrogenase was employed to increase or decrease the interior pH upon conversion of two different small-molecule substrates, thereby modulating the pH-sensitive interaction between a Ni-NTA ligand on the vesicle membrane and an oligohistidine-tagged protein in the lumen. By alternating the small-molecule substrates the interaction could be reversed.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cell mimic; liposomes; protein-ligand interactions; vesicles

Mesh：

Substances：

Year:  2015        PMID： 26089190     DOI： 10.1002/anie.201502920

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  8 in total

Review 1.  Synthetic cells in biomedical applications.

Authors:  Wakana Sato; Tomasz Zajkowski; Felix Moser; Katarzyna P Adamala
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2021-11-01

2.  Water-Insoluble Photosensitizer Nanocolloids Stabilized by Supramolecular Interfacial Assembly towards Photodynamic Therapy.

Authors:  Yamei Liu; Kai Ma; Tifeng Jiao; Ruirui Xing; Guizhi Shen; Xuehai Yan
Journal:  Sci Rep       Date:  2017-02-23       Impact factor: 4.379

Review 3.  Artificial Cells: Synthetic Compartments with Life-like Functionality and Adaptivity.

Authors:  Bastiaan C Buddingh'; Jan C M van Hest
Journal:  Acc Chem Res       Date:  2017-01-17       Impact factor: 22.384

4.  Nonequilibrium Spatiotemporal Sensing within Acoustically Patterned Two-Dimensional Protocell Arrays.

Authors:  Liangfei Tian; Mei Li; Juntai Liu; Avinash J Patil; Bruce W Drinkwater; Stephen Mann
Journal:  ACS Cent Sci       Date:  2018-11-14       Impact factor: 18.728

5.  Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis.

Authors:  Ross Eaglesfield; Mary Ann Madsen; Suparna Sanyal; Julien Reboud; Anna Amtmann
Journal:  iScience       Date:  2021-04-20

6.  Dynamic spatial and structural organization in artificial cells regulates signal processing by protein scaffolding.

Authors:  Bastiaan C Buddingh'; Antoni Llopis-Lorente; Loai K E A Abdelmohsen; Jan C M van Hest
Journal:  Chem Sci       Date:  2020-11-05       Impact factor: 9.825

Review 7.  De novo vesicle formation and growth: an integrative approach to artificial cells.

Authors:  Ahanjit Bhattacharya; Roberto J Brea; Neal K Devaraj
Journal:  Chem Sci       Date:  2017-10-26       Impact factor: 9.825

Review 8.  The hallmarks of living systems: towards creating artificial cells.

Authors:  N Amy Yewdall; Alexander F Mason; Jan C M van Hest
Journal:  Interface Focus       Date:  2018-08-17       Impact factor: 3.906
  8 in total

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