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Literature DB >> 26085249

Anti-ageing pill pushed as bona fide drug.

Erika Check Hayden.

Abstract

Mesh：

Substances：
Metformin
Glucose

Year: 2015 PMID： 26085249 DOI： 10.1038/522265a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

× No keyword cloud information.

4 in total

1. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

Authors: Richard A Miller; David E Harrison; C M Astle; Joseph A Baur; Angela Rodriguez Boyd; Rafael de Cabo; Elizabeth Fernandez; Kevin Flurkey; Martin A Javors; James F Nelson; Carlos J Orihuela; Scott Pletcher; Zelton Dave Sharp; David Sinclair; Joseph W Starnes; J Erby Wilkinson; Nancy L Nadon; Randy Strong
Journal: J Gerontol A Biol Sci Med Sci Date: 2010-10-25 Impact factor: 6.053

2. Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls.

Authors: C A Bannister; S E Holden; S Jenkins-Jones; C Ll Morgan; J P Halcox; G Schernthaner; J Mukherjee; C J Currie
Journal: Diabetes Obes Metab Date: 2014-07-31 Impact factor: 6.577

3. mTOR inhibition improves immune function in the elderly.

Authors: Joan B Mannick; Giuseppe Del Giudice; Maria Lattanzi; Nicholas M Valiante; Jens Praestgaard; Baisong Huang; Michael A Lonetto; Holden T Maecker; John Kovarik; Simon Carson; David J Glass; Lloyd B Klickstein
Journal: Sci Transl Med Date: 2014-12-24 Impact factor: 17.956

4. Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.

Authors: Brian Onken; Monica Driscoll
Journal: PLoS One Date: 2010-01-18 Impact factor: 3.240

4 in total

21 in total

Review 1. Healthy aging: The ultimate preventative medicine.

Authors: Matt Kaeberlein; Peter S Rabinovitch; George M Martin
Journal: Science Date: 2015-12-04 Impact factor: 47.728

2. The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda.

Authors: Terrie E Moffitt; Daniel W Belsky; Andrea Danese; Richie Poulton; Avshalom Caspi
Journal: J Gerontol A Biol Sci Med Sci Date: 2016-10-07 Impact factor: 6.053

3. The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin.

Authors: Emma Henriksson; Anne-Laure Huber; Erin K Soto; Anna Kriebs; Megan E Vaughan; Drew Duglan; Alanna B Chan; Stephanie J Papp; Madelena Nguyen; Megan E Afetian; Katja A Lamia
Journal: J Biol Rhythms Date: 2017-06-15 Impact factor: 3.182

Review 4. Slowing ageing by design: the rise of NAD⁺ and sirtuin-activating compounds.

Authors: Michael S Bonkowski; David A Sinclair
Journal: Nat Rev Mol Cell Biol Date: 2016-08-24 Impact factor: 94.444

5. Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment.

Authors: Tomoko Oyaizu-Toramaru; Tomohiro Suhara; Noriyo Hayakawa; Takashi Nakamura; Akiko Kubo; Shizuka Minamishima; Kyoji Yamaguchi; Takako Hishiki; Hiroshi Morisaki; Makoto Suematsu; Yoji Andrew Minamishima
Journal: Mol Cell Biol Date: 2017-07-28 Impact factor: 4.272

Anti-ageing pill pushed as bona fide drug.

1. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

2. Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls.

3. mTOR inhibition improves immune function in the elderly.

4. Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.

Review 1. Healthy aging: The ultimate preventative medicine.

2. The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda.

3. The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin.

Review 4. Slowing ageing by design: the rise of NAD⁺ and sirtuin-activating compounds.

5. Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment.

Review 6. The dog aging project: translational geroscience in companion animals.

Review 7. Energetic interventions for healthspan and resiliency with aging.

Review 8. Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules.

Review 9. Caloric restriction and exercise "mimetics'': Ready for prime time?

10. p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing.

Review 1. Healthy aging: The ultimate preventative medicine.

Review 4. Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds.

Review 6. The dog aging project: translational geroscience in companion animals.

Review 7. Energetic interventions for healthspan and resiliency with aging.

Review 8. Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules.

Review 9. Caloric restriction and exercise "mimetics'': Ready for prime time?

Review 4. Slowing ageing by design: the rise of NAD⁺ and sirtuin-activating compounds.