| Literature DB >> 26078318 |
Hubert Bassene1, Masse Sambou1, Florence Fenollar1, Siân Clarke1, Sawdiatou Djiba1, Gaël Mourembou1, Alioune Badara L Y1, Didier Raoult1, Oleg Mediannikov2.
Abstract
Large parts of African and American countries are colonized by Mansonella, a very common but poorly described filarial nematode. Bloodsucking flies of the genus Culicoides are suspected to be the vector of Mansonella perstans, but no study in Senegal has confirmed that Culicoides can transmit the parasite. Designed specific real-time quantitative polymerase chain reaction (qPCR) can be used to identify microfilaria in stained blood smears. This study was performed in July and December 2010 in the southeastern Senegal, which is known to be endemic for M. perstans. We analyzed 297 blood smears from febrile and afebrile resident people by qPCR. The global prevalence of M. perstans was approximately 14.5% in both febrile and afebrile individuals. The age group of > 30 years had the highest prevalence (22.0%). No Culicoides among 1,159 studied specimens was positive for M. perstans and its vector in Senegal still requires identification. © The American Society of Tropical Medicine and Hygiene.Entities:
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Year: 2015 PMID： 26078318 PMCID： PMC4559704 DOI： 10.4269/ajtmh.15-0051
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345