Literature DB >> 26073278

The preclinical data forum network: A new ECNP initiative to improve data quality and robustness for (preclinical) neuroscience.

Thomas Steckler1, Katja Brose2, Magali Haas3, Martien J Kas4, Elena Koustova5, Anton Bespalov6.   

Abstract

Current limitations impeding on data reproducibility are often poor statistical design, underpowered studies, lack of robust data, lack of methodological detail, biased reporting and lack of open data sharing, coupled with wrong research incentives. To improve data reproducibility, robustness and quality for brain disease research, a Preclinical Data Forum Network was formed under the umbrella of the European College of Neuropsychopharmacology (ECNP). The goal of this network, members of which met for the first time in October 2014, is to establish a forum to collaborate in precompetitive space, to exchange and develop best practices, and to bring together the members from academia, pharmaceutical industry, publishers, journal editors, funding organizations, public/private partnerships and non-profit advocacy organizations. To address the most pertinent issues identified by the Network, it was decided to establish a data sharing platform that allows open exchange of information in the area of preclinical neuroscience and to develop an educational scientific program. It is also planned to reach out to other organizations to align initiatives to enhance efficiency, and to initiate activities to improve the clinical relevance of preclinical data. Those Network activities should contribute to scientific rigor and lead to robust and relevant translational data. Here we provide a synopsis of the proceedings from the inaugural meeting.
Copyright © 2015 Elsevier B.V. and ECNP. All rights reserved.

Entities:  

Keywords:  Neuroscience; Pre-clinical; Quality assurance; Relevance; Reproducibility; Robustness

Mesh:

Year:  2015        PMID: 26073278     DOI: 10.1016/j.euroneuro.2015.05.011

Source DB:  PubMed          Journal:  Eur Neuropsychopharmacol        ISSN: 0924-977X            Impact factor:   4.600


  13 in total

Review 1.  Developing a data sharing community for spinal cord injury research.

Authors:  Alison Callahan; Kim D Anderson; Michael S Beattie; John L Bixby; Adam R Ferguson; Karim Fouad; Lyn B Jakeman; Jessica L Nielson; Phillip G Popovich; Jan M Schwab; Vance P Lemmon
Journal:  Exp Neurol       Date:  2017-05-30       Impact factor: 5.330

2.  Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets.

Authors:  Anton Bespalov; Thomas Steckler; Bruce Altevogt; Elena Koustova; Phil Skolnick; Daniel Deaver; Mark J Millan; Jesper F Bastlund; Dario Doller; Jeffrey Witkin; Paul Moser; Patricio O'Donnell; Ulrich Ebert; Mark A Geyer; Eric Prinssen; Theresa Ballard; Malcolm Macleod
Journal:  Nat Rev Drug Discov       Date:  2016-06-17       Impact factor: 84.694

3.  Systematic Review and Methodological Considerations for the Use of Single Prolonged Stress and Fear Extinction Retention in Rodents.

Authors:  Chantelle Ferland-Beckham; Lauren E Chaby; Nikolaos P Daskalakis; Dayan Knox; Israel Liberzon; Miranda M Lim; Christa McIntyre; Shane A Perrine; Victoria B Risbrough; Esther L Sabban; Andreas Jeromin; Magali Haas
Journal:  Front Behav Neurosci       Date:  2021-05-14       Impact factor: 3.558

4.  Impact of Stroke Therapy Academic Industry Roundtable (STAIR) Guidelines on Peri-Anesthesia Care for Rat Models of Stroke: A Meta-Analysis Comparing the Years 2005 and 2015.

Authors:  Aurelie Thomas; Johann Detilleux; Paul Flecknell; Charlotte Sandersen
Journal:  PLoS One       Date:  2017-01-25       Impact factor: 3.240

5.  Kinoscope: An Open-Source Computer Program for Behavioral Pharmacologists.

Authors:  Nikolaos Kokras; Dimitrios Baltas; Foivos Theocharis; Christina Dalla
Journal:  Front Behav Neurosci       Date:  2017-05-12       Impact factor: 3.558

Review 6.  Pharmacological plasticity-How do you hit a moving target?

Authors:  Michael J Parnham; Gerd Geisslinger
Journal:  Pharmacol Res Perspect       Date:  2019-11-21

7.  Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives.

Authors:  Fabrizio Grieco; Briana J Bernstein; Barbara Biemans; Lior Bikovski; C Joseph Burnett; Jesse D Cushman; Elsbeth A van Dam; Sydney A Fry; Bar Richmond-Hacham; Judith R Homberg; Martien J H Kas; Helmut W Kessels; Bastijn Koopmans; Michael J Krashes; Vaishnav Krishnan; Sreemathi Logan; Maarten Loos; Katharine E McCann; Qendresa Parduzi; Chaim G Pick; Thomas D Prevot; Gernot Riedel; Lianne Robinson; Mina Sadighi; August B Smit; William Sonntag; Reinko F Roelofs; Ruud A J Tegelenbosch; Lucas P J J Noldus
Journal:  Front Behav Neurosci       Date:  2021-09-24       Impact factor: 3.617

8.  Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Authors:  Jan Rozman; Birgit Rathkolb; Manuela A Oestereicher; Christine Schütt; Aakash Chavan Ravindranath; Stefanie Leuchtenberger; Sapna Sharma; Martin Kistler; Monja Willershäuser; Robert Brommage; Terrence F Meehan; Jeremy Mason; Hamed Haselimashhadi; Tertius Hough; Ann-Marie Mallon; Sara Wells; Luis Santos; Christopher J Lelliott; Jacqueline K White; Tania Sorg; Marie-France Champy; Lynette R Bower; Corey L Reynolds; Ann M Flenniken; Stephen A Murray; Lauryl M J Nutter; Karen L Svenson; David West; Glauco P Tocchini-Valentini; Arthur L Beaudet; Fatima Bosch; Robert B Braun; Michael S Dobbie; Xiang Gao; Yann Herault; Ala Moshiri; Bret A Moore; K C Kent Lloyd; Colin McKerlie; Hiroshi Masuya; Nobuhiko Tanaka; Paul Flicek; Helen E Parkinson; Radislav Sedlacek; Je Kyung Seong; Chi-Kuang Leo Wang; Mark Moore; Steve D Brown; Matthias H Tschöp; Wolfgang Wurst; Martin Klingenspor; Eckhard Wolf; Johannes Beckers; Fausto Machicao; Andreas Peter; Harald Staiger; Hans-Ulrich Häring; Harald Grallert; Monica Campillos; Holger Maier; Helmut Fuchs; Valerie Gailus-Durner; Thomas Werner; Martin Hrabe de Angelis
Journal:  Nat Commun       Date:  2018-01-18       Impact factor: 17.694

Review 9.  What incentives increase data sharing in health and medical research? A systematic review.

Authors:  Anisa Rowhani-Farid; Michelle Allen; Adrian G Barnett
Journal:  Res Integr Peer Rev       Date:  2017-05-05

Review 10.  The Use of ex Vivo Rodent Platforms in Neuroscience Translational Research With Attention to the 3Rs Philosophy.

Authors:  Laura Lossi; Adalberto Merighi
Journal:  Front Vet Sci       Date:  2018-07-19
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