| Literature DB >> 26068056 |
Jason D Wright1,2,3, Ana I Tergas1,2,3,4, Cande V Ananth1,4, William M Burke1,2,3, June Y Hou1,2,3, Ling Chen1, Alfred I Neugut2,3,4,5, Catherine A Richards4, Dawn L Hershman2,3,4,5.
Abstract
Using a nationwide database, 4,874 patients with hypercalcemia of malignancy were identified. The in-hospital mortality rate was 6.8%. Overall, 1,971 (40.4%) patients received pamidronate and 1,399 (28.7%) received zoledronic acid during hospitalization. Calcitonin was utilized in 1,337 (27.4%) patients while glucocorticoids were administered to 1,311 (26.9%). Use of contraindicated medications was noted in 136 (2.8%) patients who received thiazide diuretics and 12 (0.2%) who received lithium. Tumor site, presence of bone metastases, and severity of illness were predictors of treatment. There was no association between treatment with bisphosphonates, calcitonin, or glucocorticoids and morbidity or mortality.Entities:
Keywords: Calcium; Hypercalcemia; Malignancy
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Year: 2015 PMID： 26068056 PMCID： PMC4666677 DOI： 10.3109/07357907.2015.1047506
Source DB: PubMed Journal: Cancer Invest ISSN： 0735-7907 Impact factor: 2.176