Literature DB >> 26062507

Population genomics of Bronze Age Eurasia.

Morten E Allentoft1, Martin Sikora1, Karl-Göran Sjögren2, Simon Rasmussen3, Morten Rasmussen1, Jesper Stenderup1, Peter B Damgaard1, Hannes Schroeder4, Torbjörn Ahlström5, Lasse Vinner1, Anna-Sapfo Malaspinas1, Ashot Margaryan1, Tom Higham6, David Chivall6, Niels Lynnerup7, Lise Harvig7, Justyna Baron8, Philippe Della Casa9, Paweł Dąbrowski10, Paul R Duffy11, Alexander V Ebel12, Andrey Epimakhov13, Karin Frei14, Mirosław Furmanek8, Tomasz Gralak8, Andrey Gromov15, Stanisław Gronkiewicz16, Gisela Grupe17, Tamás Hajdu18, Radosław Jarysz19, Valeri Khartanovich15, Alexandr Khokhlov20, Viktória Kiss21, Jan Kolář22, Aivar Kriiska23, Irena Lasak8, Cristina Longhi24, George McGlynn17, Algimantas Merkevicius25, Inga Merkyte26, Mait Metspalu27, Ruzan Mkrtchyan28, Vyacheslav Moiseyev15, László Paja29, György Pálfi30, Dalia Pokutta2, Łukasz Pospieszny31, T Douglas Price32, Lehti Saag27, Mikhail Sablin33, Natalia Shishlina34, Václav Smrčka35, Vasilii I Soenov36, Vajk Szeverényi21, Gusztáv Tóth37, Synaru V Trifanova36, Liivi Varul23, Magdolna Vicze38, Levon Yepiskoposyan39, Vladislav Zhitenev40, Ludovic Orlando1, Thomas Sicheritz-Pontén3, Søren Brunak41, Rasmus Nielsen42, Kristian Kristiansen2, Eske Willerslev1.   

Abstract

The Bronze Age of Eurasia (around 3000-1000 BC) was a period of major cultural changes. However, there is debate about whether these changes resulted from the circulation of ideas or from human migrations, potentially also facilitating the spread of languages and certain phenotypic traits. We investigated this by using new, improved methods to sequence low-coverage genomes from 101 ancient humans from across Eurasia. We show that the Bronze Age was a highly dynamic period involving large-scale population migrations and replacements, responsible for shaping major parts of present-day demographic structure in both Europe and Asia. Our findings are consistent with the hypothesized spread of Indo-European languages during the Early Bronze Age. We also demonstrate that light skin pigmentation in Europeans was already present at high frequency in the Bronze Age, but not lactose tolerance, indicating a more recent onset of positive selection on lactose tolerance than previously thought.

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Year:  2015        PMID: 26062507     DOI: 10.1038/nature14507

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  39 in total

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Journal:  Nature       Date:  2013-06-26       Impact factor: 49.962

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Journal:  Nature       Date:  2014-09-18       Impact factor: 49.962

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  342 in total

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7.  DNA deluge reveals Bronze Age secrets.

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8.  Insights into matrilineal genetic structure, differentiation and ancestry of Armenians based on complete mitogenome data.

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9.  Inference of Population Structure from Time-Series Genotype Data.

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Review 10.  Recent advances in the study of fine-scale population structure in humans.

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