Literature DB >> 26061114

Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level.

A H Okholm1, H Aslan, F Besenbacher, M Dong, J Kjems.   

Abstract

DNA origami has been used to orchestrate reactions with nano-precision using a variety of biomolecules. Here, the dynamics of albumin-assisted, localized single-molecule DNA polymerization by terminal deoxynucleotidyl transferase on a 2D DNA origami are monitored using AFM in liquid. Direct visualization of the surface activity revealed the mechanics of growth.

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Year:  2015        PMID: 26061114     DOI: 10.1039/c5nr01945a

Source DB:  PubMed          Journal:  Nanoscale        ISSN: 2040-3364            Impact factor:   7.790


  2 in total

1.  Enzymatic synthesis and modification of high molecular weight DNA using terminal deoxynucleotidyl transferase.

Authors:  Sonal Deshpande; Yunqi Yang; Ashutosh Chilkoti; Stefan Zauscher
Journal:  Methods Enzymol       Date:  2019-08-30       Impact factor: 1.600

2.  Programmable Site-Specific Functionalization of DNA Origami with Polynucleotide Brushes.

Authors:  Yunqi Yang; Qinyi Lu; Chao-Min Huang; Hongji Qian; Yunlong Zhang; Sonal Deshpande; Gaurav Arya; Yonggang Ke; Stefan Zauscher
Journal:  Angew Chem Int Ed Engl       Date:  2021-08-24       Impact factor: 16.823

  2 in total

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