Literature DB >> 26060490

Is there any relationship between RDW levels and atrial fibrillation in hypertensive patient?

Savas Sarikaya1, Şafak Şahin2, Lütfi Akyol3, Elif Börekçi3, Yunus Keser Yilmaz4, Fatih Altunkaş5, Kayihan Karaman5.   

Abstract

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke and death. Patients with hypertensive have an increased risk of developing atrial fibrillation. RDW (Red blood cell distribution width) levels are elevated in cardiovascular disorders including heart failure, stable coronary disease, acute coronary syndrome, slow coronary flow and stroke.
OBJECTIVE: We aimed to investigate the relation between RDW and AF in patients with hypertensive.
METHOD: We retrospectively examined 126 consecutive hypertensive patients (63 hypertensive patients with AF and 63 hypertensive patients without AF matched with age and sex.
RESULTS: The mean age of the study population was 71,09± 8,50 (af group) and 70,97±8,24 (non-af group) years. RDW level was different among patients with atrial fibrillation and without atrial fibrillation.(15,13±1,58 and 14,05±1,15 p<001) . Logistic regression analysis showed that RDW and left atrial dimension were only independently risk factory associated with atrial fibrillation. (Rdw odds ratio:1,846 CI; 1,221-2,793 p<0,05). Roc curve analyses were applied to determine the cut-off point. Cut-off point was at 14,195 and Sensitive, specificity was %71,4, %56 respectively.
CONCLUSION: RDW levels were higher in hypertensive patients with atrial fibrillation. An increased RDW level in the patient with hypertension may alert physician on developing or presence of atrial fibrillation.

Entities:  

Keywords:  atrial fibrillation; hypertension; red blood cell distribution width

Mesh:

Substances:

Year:  2014        PMID: 26060490      PMCID: PMC4449072          DOI: 10.4314/ahs.v14i1.41

Source DB:  PubMed          Journal:  Afr Health Sci        ISSN: 1680-6905            Impact factor:   0.927


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