Literature DB >> 26060464

A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume.

Fahrettin Talay1, Tarık Ocak2, Aytekin Alcelik3, Kurşat Erkuran2, Akcan Akkaya4, Arif Duran2, Abdullah Demirhan4, Ozlem Kar Kurt1, Zehra Asuk1.   

Abstract

OBJECTIVE: To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).
METHODS: Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.
RESULTS: A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).
CONCLUSIONS: MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.

Entities:  

Keywords:  Acute pulmonary embolism; emergency department; mean platelet volume; thrombus

Mesh:

Substances:

Year:  2014        PMID: 26060464      PMCID: PMC4449081          DOI: 10.4314/ahs.v14i1.15

Source DB:  PubMed          Journal:  Afr Health Sci        ISSN: 1680-6905            Impact factor:   0.927


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