BACKGROUND: Pulmonary thromboembolism is a serious complication in patients with deep vein thrombosis (DVT). Previous studies have demonstrated that platelet activation occurs in patients with DVT. Mean platelet volume (MPV) is a simple and easy method of assessing platelet function. The aim of this study was to assess the MPV, an indicator of platelet activation in patients with DVT. PATIENTS AND METHODS: The study group consisted of 52 patients with newly diagnosed acute DVT. An age-, gender-, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent ultrasonographic examination. We measured the serum MPV values in patients with DVT and control participants. RESULTS: Mean platelet volume was significantly higher among patients with DVT when compared with the control group (8.6 ± 0.8 vs 7.7 ± 0.9 fL, respectively; P < .001). CONCLUSION: We have shown that MPV was significantly elevated in patients with DVT compared to controls.
BACKGROUND:Pulmonary thromboembolism is a serious complication in patients with deep vein thrombosis (DVT). Previous studies have demonstrated that platelet activation occurs in patients with DVT. Mean platelet volume (MPV) is a simple and easy method of assessing platelet function. The aim of this study was to assess the MPV, an indicator of platelet activation in patients with DVT. PATIENTS AND METHODS: The study group consisted of 52 patients with newly diagnosed acute DVT. An age-, gender-, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent ultrasonographic examination. We measured the serum MPV values in patients with DVT and control participants. RESULTS: Mean platelet volume was significantly higher among patients with DVT when compared with the control group (8.6 ± 0.8 vs 7.7 ± 0.9 fL, respectively; P < .001). CONCLUSION: We have shown that MPV was significantly elevated in patients with DVT compared to controls.
Authors: Yasin Sarıkaya; Cem Bayraktar; Mehmet Karataş; Sedat Doğan; Serdar Olt; Emin Kaskalan; İbrahim Halil Türkbeyler Journal: Eur Arch Otorhinolaryngol Date: 2016-03-28 Impact factor: 2.503
Authors: Jun Yang; Xuan Zhou; Xiaorong Fan; Min Xiao; Dinghua Yang; Bo Liang; Meng Dai; Lanlan Shan; Jingbo Lu; Zhiqi Lin; Rong Liu; Jun Liu; Liping Wang; Mei Zhong; Yu Jiang; Xiaochun Bai Journal: Blood Date: 2016-06-10 Impact factor: 22.113