Literature DB >> 26059788

[Personalized medicine in otology. The role of genetic diagnostics in patients with hearing impairment].

N Friese1, K Braun, M Müller, A Tropitzsch.   

Abstract

BACKGROUND: Classification of diseases on the molecular level is the basis for personalized medicine. Personalized medicine proposes to improve efficiency and quality of care, to reduce side effects and to increase long-term cost-effectiveness.
OBJECTIVES: This paper is concerned with the role of genetic diagnostics in patients with a cochlear implant.
MATERIAL AND METHODS: A selective literature search in PubMed was performed.
RESULTS: Genetic diagnosis allows ruling out syndromic hearing loss and thus prevents follow-up studies. It allows genetic counseling, prognosis and advice on family planning and targeted prevention. Due to its minimal invasiveness, it is suitable for evaluation of factors accounting for hearing loss in children.
CONCLUSIONS: Molecular medicine plays a major role in the treatment of sensorineural hearings loss with cochlear implants.

Entities:  

Mesh:

Year:  2015        PMID: 26059788     DOI: 10.1007/s00106-015-0013-x

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  21 in total

Review 1.  Deafness in the genomics era.

Authors:  A Eliot Shearer; Michael S Hildebrand; Christina M Sloan; Richard J H Smith
Journal:  Hear Res       Date:  2011-10-08       Impact factor: 3.208

Review 2.  Forty-six genes causing nonsyndromic hearing impairment: which ones should be analyzed in DNA diagnostics?

Authors:  Nele Hilgert; Richard J H Smith; Guy Van Camp
Journal:  Mutat Res       Date:  2008-08-29       Impact factor: 2.433

3.  A post-hoc comparison of the utility of sanger sequencing and exome sequencing for the diagnosis of heterogeneous diseases.

Authors:  Kornelia Neveling; Ilse Feenstra; Christian Gilissen; Lies H Hoefsloot; Erik-Jan Kamsteeg; Arjen R Mensenkamp; Richard J T Rodenburg; Helger G Yntema; Liesbeth Spruijt; Sascha Vermeer; Tuula Rinne; Koen L van Gassen; Danielle Bodmer; Dorien Lugtenberg; Rick de Reuver; Wendy Buijsman; Ronny C Derks; Nienke Wieskamp; Bert van den Heuvel; Marjolijn J L Ligtenberg; Hannie Kremer; David A Koolen; Bart P C van de Warrenburg; Frans P M Cremers; Carlo L M Marcelis; Jan A M Smeitink; Saskia B Wortmann; Wendy A G van Zelst-Stams; Joris A Veltman; Han G Brunner; Hans Scheffer; Marcel R Nelen
Journal:  Hum Mutat       Date:  2013-10-18       Impact factor: 4.878

4.  Genetic characteristics in children with cochlear implants and the corresponding auditory performance.

Authors:  Chen-Chi Wu; Tien-Chen Liu; Shih-Hao Wang; Chuan-Jen Hsu; Che-Ming Wu
Journal:  Laryngoscope       Date:  2011-05-06       Impact factor: 3.325

5.  Advancing genetic testing for deafness with genomic technology.

Authors:  A Eliot Shearer; E Ann Black-Ziegelbein; Michael S Hildebrand; Robert W Eppsteiner; Harini Ravi; Swati Joshi; Angelica C Guiffre; Christina M Sloan; Scott Happe; Susanna D Howard; Barbara Novak; Adam P Deluca; Kyle R Taylor; Todd E Scheetz; Terry A Braun; Thomas L Casavant; William J Kimberling; Emily M Leproust; Richard J H Smith
Journal:  J Med Genet       Date:  2013-06-26       Impact factor: 6.318

6.  GJB2 mutations and degree of hearing loss: a multicenter study.

Authors:  Rikkert L Snoeckx; Patrick L M Huygen; Delphine Feldmann; Sandrine Marlin; Françoise Denoyelle; Jaroslaw Waligora; Malgorzata Mueller-Malesinska; Agneszka Pollak; Rafal Ploski; Alessandra Murgia; Eva Orzan; Pierangela Castorina; Umberto Ambrosetti; Ewa Nowakowska-Szyrwinska; Jerzy Bal; Wojciech Wiszniewski; Andreas R Janecke; Doris Nekahm-Heis; Pavel Seeman; Olga Bendova; Margaret A Kenna; Anna Frangulov; Heidi L Rehm; Mustafa Tekin; Armagan Incesulu; Hans-Henrik M Dahl; Desirée du Sart; Lucy Jenkins; Deirdre Lucas; Maria Bitner-Glindzicz; Karen B Avraham; Zippora Brownstein; Ignacio del Castillo; Felipe Moreno; Nikolaus Blin; Markus Pfister; Istvan Sziklai; Timea Toth; Philip M Kelley; Edward S Cohn; Lionel Van Maldergem; Pascale Hilbert; Anne-Françoise Roux; Michel Mondain; Lies H Hoefsloot; Cor W R J Cremers; Tuija Löppönen; Heikki Löppönen; Agnete Parving; Karen Gronskov; Iris Schrijver; Joseph Roberson; Francesca Gualandi; Alessandro Martini; Geneviéve Lina-Granade; Nathalie Pallares-Ruiz; Céu Correia; Graça Fialho; Kim Cryns; Nele Hilgert; Paul Van de Heyning; Carla J Nishimura; Richard J H Smith; Guy Van Camp
Journal:  Am J Hum Genet       Date:  2005-10-19       Impact factor: 11.025

7.  AudioGene: predicting hearing loss genotypes from phenotypes to guide genetic screening.

Authors:  Kyle R Taylor; Adam P Deluca; A Eliot Shearer; Michael S Hildebrand; E Ann Black-Ziegelbein; V Nikhil Anand; Christina M Sloan; Robert W Eppsteiner; Todd E Scheetz; Patrick L M Huygen; Richard J H Smith; Terry A Braun; Thomas L Casavant
Journal:  Hum Mutat       Date:  2013-02-19       Impact factor: 4.878

8.  Predominance of genetic diagnosis and imaging results as predictors in determining the speech perception performance outcome after cochlear implantation in children.

Authors:  Chen-Chi Wu; Yi-Chin Lee; Pei-Jer Chen; Chuan-Jen Hsu
Journal:  Arch Pediatr Adolesc Med       Date:  2008-03

Review 9.  The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine.

Authors:  Peter D Stenson; Matthew Mort; Edward V Ball; Katy Shaw; Andrew Phillips; David N Cooper
Journal:  Hum Genet       Date:  2014-01       Impact factor: 4.132

10.  Exploration of molecular genetic etiology for Korean cochlear implantees with severe to profound hearing loss and its implication.

Authors:  Joo Hyun Park; Nayoung K D Kim; Ah Reum Kim; Jihye Rhee; Seung Ha Oh; Ja-Won Koo; Jae-Yong Nam; Woong-Yang Park; Byung Yoon Choi
Journal:  Orphanet J Rare Dis       Date:  2014-11-06       Impact factor: 4.123

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  1 in total

1.  Special issues for the 55th Inner Ear Biology Workshop 06.-08.09.2018 in Berlin : Basic research and clinical aspects-translational aspects of hearing research.

Authors:  B Mazurek; M Knipper; E Biesinger; H Schulze
Journal:  HNO       Date:  2019-06       Impact factor: 1.284

  1 in total

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