Literature DB >> 26055459

Clinical and pathological analysis of renal damage in elderly patients with type 2 diabetes mellitus.

Shuang-Tong Yan1, Jun-Yan Liu2, Hui Tian3, Chun-Lin Li1, Jian Li1, Ying-Hong Shao1, Huai-Yin Shi4, Yu Liu1, Yan-Ping Gong1, Fu-Sheng Fang1, Ban-Ruo Sun1.   

Abstract

The aim of this study was to investigate the causes and influential factors of renal damage in elderly patients with type 2 diabetes mellitus (T2DM). Clinical data and pathological findings at autopsy of 161 elderly T2DM patients died between October 1994 and August 2011 were retrospectively reviewed. The mean age of these patients was 80.8 ± 8.3 years (range 60-105 years). The incidences of diabetic nephropathy (DN), non-diabetic renal diseases (NDRD), and DN complicated with NDRD were 31.1, 62.7, and 16.2 %, respectively. In patients with NDRD, the incidence of hypertensive renal damage (HRD) was 54.7 %. In the factors causing renal damage, DN and NDRD accounted for 1/3 and 2/3, respectively. HRD accounted for the largest proportion of NDRD. Blood pressure control may provide additional benefits for elderly T2DM patients by preventing and delaying the occurrence and development of renal disease.

Entities:  

Keywords:  Autopsy; Diabetes mellitus; Elderly; Renal damage

Mesh：

Year:  2015        PMID： 26055459     DOI： 10.1007/s10238-015-0362-5

Source DB:  PubMed          Journal:  Clin Exp Med        ISSN： 1591-8890            Impact factor:   3.984


  21 in total

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Journal:  Int Urol Nephrol       Date:  2016-06-06       Impact factor: 2.370

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5.  Clinicopathological Features of Nondiabetic Renal Diseases from Different Age Groups: An Observational Cross-sectional Study.

Authors:  Xiao-Min Liu; Qian Wang; Zhe-Yi Dong; Wei-Guang Zhang; Guang-Yan Cai; Li Zhang; Yong Wang; Han-Yu Zhu; Li Tang; Wan-Jun Shen; Xiang-Mei Chen
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Journal:  Hum Pathol       Date:  2018-11-27       Impact factor: 3.466

7.  Potential Role of the Renal Arterial Resistance Index in the Differential Diagnosis of Diabetic Kidney Disease.

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8.  The modern spectrum of biopsy-proven renal disease in Chinese diabetic patients-a retrospective descriptive study.

Authors:  Diankun Liu; Ting Huang; Nan Chen; Gang Xu; Ping Zhang; Yang Luo; Yongping Wang; Tao Lu; Long Wang; Mengqi Xiong; Jian Geng; Sheng Nie
Journal:  PeerJ       Date:  2018-03-27       Impact factor: 2.984
  8 in total

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