Literature DB >> 26055047

Celastrol identified as a leptin sensitizer and potential novel treatment for obesity.

Claire Greenhill.   

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Year:  2015        PMID： 26055047     DOI： 10.1038/nrendo.2015.94

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


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  1 in total

1.  Treatment of obesity with celastrol.

Authors:  Junli Liu; Jaemin Lee; Mario Andres Salazar Hernandez; Ralph Mazitschek; Umut Ozcan
Journal:  Cell       Date:  2015-05-21       Impact factor: 41.582
  1 in total
  9 in total

Review 1.  Recent evidence in support of traditional chinese medicine to restore normal leptin function in simple obesity.

Authors:  Jialin Shao; Chen Li; Litao Bai; Xiaolin Ni; Shaoqin Ge; Jinghui Zhang; Hanqing Zhao
Journal:  Heliyon       Date:  2022-05-19

2.  Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways.

Authors:  Dan Luo; Yumeng Guo; Yuanyuan Cheng; Jia Zhao; Yu Wang; Jianhui Rong
Journal:  Aging (Albany NY)       Date:  2017-10-16       Impact factor: 5.682

Review 3.  A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F.

Authors:  Shao-Ru Chen; Yan Dai; Jing Zhao; Ligen Lin; Yitao Wang; Ying Wang
Journal:  Front Pharmacol       Date:  2018-02-14       Impact factor: 5.810

Review 4.  Characteristics of Nur77 and its ligands as potential anticancer compounds (Review).

Authors:  Lingjuan Wu; Liqun Chen
Journal:  Mol Med Rep       Date:  2018-09-27       Impact factor: 2.952

5.  Angiopoietin-Like Growth Factor Involved in Leptin Signaling in the Hypothalamus.

Authors:  Yunseon Jang; Jun Young Heo; Min Joung Lee; Jiebo Zhu; Changjun Seo; Da Hyun Go; Sung Kyung Yoon; Date Yukari; Yuichi Oike; Jong-Woo Sohn; Minho Shong; Gi Ryang Kweon
Journal:  Int J Mol Sci       Date:  2021-03-26       Impact factor: 5.923

6.  PERK in POMC neurons connects celastrol with metabolism.

Authors:  Zhenyan He; Linh Lieu; Yanbin Dong; Sadia Afrin; Dominic Chau; Anita Kabahizi; Briana Wallace; Jianhong Cao; Eun-Sang Hwang; Ting Yao; Yiru Huang; Jennifer Okolo; Bo Cheng; Yong Gao; Ling Hu; Kevin W Williams
Journal:  JCI Insight       Date:  2021-09-22

Review 7.  Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI.

Authors:  Faheem Mustafa; Hitesh Chopra; Atif Amin Baig; Satya Kumar Avula; Sony Kumari; Tapan Kumar Mohanta; Muthupandian Saravanan; Awdhesh Kumar Mishra; Nanaocha Sharma; Yugal Kishore Mohanta
Journal:  J Fungi (Basel)       Date:  2022-02-21

8.  Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice.

Authors:  Dan Luo; Ni Fan; Xiuying Zhang; Fung Yin Ngo; Jia Zhao; Wei Zhao; Ming Huang; Ding Li; Yu Wang; Jianhui Rong
Journal:  Elife       Date:  2022-02-09       Impact factor: 8.140

9.  Genetic Transformation System for Woody Plant Tripterygium wilfordii and Its Application to Product Natural Celastrol.

Authors:  Yujun Zhao; Yifeng Zhang; Ping Su; Jian Yang; Luqi Huang; Wei Gao
Journal:  Front Plant Sci       Date:  2018-01-09       Impact factor: 5.753
  9 in total

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