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Literature DB >> 19095631

Prostanoids in health and disease.

Emer M Smyth¹, Tilo Grosser, Miao Wang, Ying Yu, Garret A FitzGerald.

Abstract

The prostanoids are a family of lipid mediators generated by the action of cyclooxygenase on a 20-carbon unsaturated fatty acid, arachidonic acid. Prostanoids are generated widely in response to diverse stimuli and, acting in a paracrine or autocrine manner, play important roles in normal physiology and disease. This review summarizes the current knowledge on prostanoid generation and the roles of individual mediators, their biosynthetic pathways, and their receptors in health and disease.

Entities: Chemical

Mesh：

Substances：

Year: 2008 PMID： 19095631 PMCID： PMC2674745 DOI： 10.1194/jlr.R800094-JLR200

Source DB: PubMed Journal: J Lipid Res ISSN： 0022-2275 Impact factor: 5.922

48 in total

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Authors: G A FitzGerald
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Journal: JAMA Date: 2006-09-12 Impact factor: 56.272

4. COX-2-derived prostacyclin confers atheroprotection on female mice.

Authors: Karine M Egan; John A Lawson; Susanne Fries; Beverley Koller; Daniel J Rader; Emer M Smyth; Garret A Fitzgerald
Journal: Science Date: 2004-11-18 Impact factor: 47.728

5. Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis.

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Journal: Nat Neurosci Date: 2003-10-19 Impact factor: 24.884

6. Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation.

Authors: Stephen J Wilson; Aoife M Roche; Ekaterina Kostetskaia; Emer M Smyth
Journal: J Biol Chem Date: 2004-10-07 Impact factor: 5.157

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Authors: Samuel S Fam; Jason D Morrow
Journal: Curr Med Chem Date: 2003-09 Impact factor: 4.530

8. Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice.

Authors: Takuya Kobayashi; Yoshio Tahara; Mayumi Matsumoto; Masako Iguchi; Hideto Sano; Toshinori Murayama; Hidenori Arai; Hiroji Oida; Takami Yurugi-Kobayashi; Jun K Yamashita; Hiroyuki Katagiri; Masataka Majima; Masayuki Yokode; Toru Kita; Shuh Narumiya
Journal: J Clin Invest Date: 2004-09 Impact factor: 14.808

Review 9. Cyclooxygenase-2 and inflammation in atherosclerosis.

Authors: MacRae F Linton; Sergio Fazio
Journal: Curr Opin Pharmacol Date: 2004-04 Impact factor: 5.547

Review 10. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation.

Authors: Aaron N Hata; Richard M Breyer
Journal: Pharmacol Ther Date: 2004-08 Impact factor: 12.310

167 in total

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Review 2. The electrophile responsive proteome: integrating proteomics and lipidomics with cellular function.

Authors: Ashlee N Higdon; Aimee Landar; Stephen Barnes; Victor M Darley-Usmar
Journal: Antioxid Redox Signal Date: 2012-04-18 Impact factor: 8.401

3. Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Authors: Laura E Fredenburgh; Margarita M Suárez Velandia; Jun Ma; Torsten Olszak; Manuela Cernadas; Joshua A Englert; Su Wol Chung; Xiaoli Liu; Cynthia Begay; Robert F Padera; Richard S Blumberg; Stephen R Walsh; Rebecca M Baron; Mark A Perrella
Journal: J Immunol Date: 2011-10-03 Impact factor: 5.422

4. Serum concentrations of cyclooxygenase-2 in patients with systemic sclerosis: association with lower frequency of pulmonary fibrosis.

Authors: Iman H Bassyouni; Roba M Talaat; Tarek A Salem
Journal: J Clin Immunol Date: 2011-10-07 Impact factor: 8.317

5. Seeing the future of bioactive lipid drug targets.

Authors: Jilly F Evans; John H Hutchinson
Journal: Nat Chem Biol Date: 2010-07 Impact factor: 15.040

6. Roles of affinity and lipophilicity in the slow kinetics of prostanoid receptor antagonists on isolated smooth muscle preparations.

Authors: R L Jones; D F Woodward; J W Wang; R L Clark
Journal: Br J Pharmacol Date: 2011-02 Impact factor: 8.739

7. Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence.

Authors: Oleh Lushchak; Veronika Piskovatska; Olha Strilbytska; Iryna Kindrat; Nadya Stefanyshyn; Alexander Koliada; Volodymyr Bubalo; Kenneth B Storey; Alexander Vaiserman
Journal: Adv Exp Med Biol Date: 2021 Impact factor: 2.622

Review 8. Understanding inflammatory pain: ion channels contributing to acute and chronic nociception.

Authors: John E Linley; Kirstin Rose; Lezanne Ooi; Nikita Gamper
Journal: Pflugers Arch Date: 2010-02-17 Impact factor: 3.657

9. Impact of a Standard Rodent Chow Diet on Tissue n-6 Fatty Acids, Δ9-Desaturation Index, and Plasmalogen Mass in Rats Fed for One Year.

Authors: F Pédrono; N Boulier-Monthéan; D Catheline; P Legrand
Journal: Lipids Date: 2015-09-19 Impact factor: 1.880

10. Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles.

Authors: Yong Ma; Song Gao; Ming Hu
Journal: J Chromatogr B Analyt Technol Biomed Life Sci Date: 2015-07-19 Impact factor: 3.205