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Literature DB >> 26044285

Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels.

Cathal J Kearney¹, Hadas Skaat¹, Stephen M Kennedy¹, Jennifer Hu¹, Max Darnell¹, Theresa M Raimondo¹, David J Mooney¹.

Abstract

Natural biological processes are intricately controlled by the timing and spatial distribution of various cues. To mimic this precise level of control, the physical sizes of gold nanoparticles are utilized to sterically entrap them in hydrogel materials, where they are subsequently released only in response to ultrasound. These nanoparticles can transport bioactive factors to cells and direct cell behavior on-demand.

Entities: Chemical Disease Gene Species

Keywords: gold nanoparticles; on-demand release; self-healing alginate; ultrasound

Mesh：

Substances：

Year: 2015 PMID： 26044285 PMCID： PMC4685946 DOI： 10.1002/adhm.201500254

Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933

29 in total

1. Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis.

Authors: Jaeyun Kim; Lan Cao; Dmitry Shvartsman; Eduardo A Silva; David J Mooney
Journal: Nano Lett Date: 2010-12-30 Impact factor: 11.189

2. Ultrasound-enhanced polymer degradation and release of incorporated substances.

Authors: J Kost; K Leong; R Langer
Journal: Proc Natl Acad Sci U S A Date: 1989-10 Impact factor: 11.205

Review 3. Stimuli-responsive nanocarriers for drug delivery.

Authors: Simona Mura; Julien Nicolas; Patrick Couvreur
Journal: Nat Mater Date: 2013-11 Impact factor: 43.841

4. Synthesis and surface modification of highly monodispersed, spherical gold nanoparticles of 50-200 nm.

Authors: Steven D Perrault; Warren C W Chan
Journal: J Am Chem Soc Date: 2009-12-02 Impact factor: 15.419

5. An integrated microrobotic platform for on-demand, targeted therapeutic interventions.

Authors: Stefano Fusco; Mahmut Selman Sakar; Stephen Kennedy; Christian Peters; Rocco Bottani; Fabian Starsich; Angelo Mao; Georgios A Sotiriou; Salvador Pané; Sotiris E Pratsinis; David Mooney; Bradley J Nelson
Journal: Adv Mater Date: 2013-11-04 Impact factor: 30.849

Review 6. Colloidal gold: a novel nanoparticle for targeted cancer therapeutics.

Authors: Anathea C Powell; Giulio F Paciotti; Steven K Libutti
Journal: Methods Mol Biol Date: 2010

7. Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution.

Authors: C Scheufler; W Sebald; M Hülsmeyer
Journal: J Mol Biol Date: 1999-03-19 Impact factor: 5.469

8. Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.

Authors: Nathaniel Huebsch; Cathal J Kearney; Xuanhe Zhao; Jaeyun Kim; Christine A Cezar; Zhigang Suo; David J Mooney
Journal: Proc Natl Acad Sci U S A Date: 2014-06-24 Impact factor: 11.205

9. Size-dependent in vivo toxicity of PEG-coated gold nanoparticles.

Authors: Xiao-Dong Zhang; Di Wu; Xiu Shen; Pei-Xun Liu; Na Yang; Bin Zhao; Hao Zhang; Yuan-Ming Sun; Liang-An Zhang; Fei-Yue Fan
Journal: Int J Nanomedicine Date: 2011-09-20

10. Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition.

Authors: Aaron Goldman; Biswanath Majumder; Andrew Dhawan; Sudharshan Ravi; David Goldman; Mohammad Kohandel; Pradip K Majumder; Shiladitya Sengupta
Journal: Nat Commun Date: 2015-02-11 Impact factor: 14.919

11 in total

1. Designing hydrogels for controlled drug delivery.

Authors: Jianyu Li; David J Mooney
Journal: Nat Rev Mater Date: 2016-10-18 Impact factor: 66.308

Review 2. Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications.

Authors: Hussein M El-Husseiny; Eman A Mady; Lina Hamabe; Amira Abugomaa; Kazumi Shimada; Tomohiko Yoshida; Takashi Tanaka; Aimi Yokoi; Mohamed Elbadawy; Ryou Tanaka
Journal: Mater Today Bio Date: 2021-12-09

Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels.

1. Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis.

2. Ultrasound-enhanced polymer degradation and release of incorporated substances.

Review 3. Stimuli-responsive nanocarriers for drug delivery.

4. Synthesis and surface modification of highly monodispersed, spherical gold nanoparticles of 50-200 nm.

5. An integrated microrobotic platform for on-demand, targeted therapeutic interventions.

Review 6. Colloidal gold: a novel nanoparticle for targeted cancer therapeutics.

7. Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution.

8. Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.

9. Size-dependent in vivo toxicity of PEG-coated gold nanoparticles.

10. Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition.

1. Designing hydrogels for controlled drug delivery.

Review 2. Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications.

Review 3. Engineering the next generation of cell-based therapeutics.

4. Sequential release of nanoparticle payloads from ultrasonically burstable capsules.

Review 5. Biofabricating Functional Soft Matter Using Protein Engineering to Enable Enzymatic Assembly.

Review 6. Active biomaterials for mechanobiology.

7. Metabolic labeling and targeted modulation of dendritic cells.

8. Pulsatile Chemotherapeutic Delivery Profiles Using Magnetically Responsive Hydrogels.

Review 9. Layer-by-Layer Cell Encapsulation for Drug Delivery: The History, Technique Basis, and Applications.

Review 10. Stimuli-Responsive Drug Release from Smart Polymers.