Literature DB >> 26044121

Clinical value of SPECT/CT in the painful total knee arthroplasty (TKA): a prospective study in a consecutive series of 100 TKA.

Michael T Hirschmann1, Felix Amsler2, Helmut Rasch3.   

Abstract

PURPOSE: Bone single photon emission computed tomography (SPECT)/CT is considered as beneficial in unhappy patients with pain, stiffness or swelling after total knee arthroplasty (TKA). The purpose of this study was to identify typical patterns of bone tracer uptake (BTU), distribution and intensity values in patients after TKA. The above findings were correlated with the type and fixation of TKA, the time from TKA and intraoperative findings at revision surgery.
METHODS: A total of 100 knees of 84 consecutive patients (mean age ± SD 70 ± 11 years) after TKA with persistent knee pain were prospectively included. All patients underwent clinical examination, standardized radiographs and (99m)Tc-hydroxymethane diphosphonate (HDP) SPECT/CT as part of a routine diagnostic algorithm. The diagnosis before and after SPECT/CT and final treatment were recorded. TKA component position was determined on 3-D reconstructed images. Intensity and anatomical distribution of BTU was determined. Maximum intensity values were recorded as well as ratios in relation to the proximal midshaft of the femur. Univariate analyses (chi-square test, Pearson's correlation and t test for independent samples) were performed (p < 0.05).
RESULTS: SPECT/CT changed the clinical diagnosis and final treatment in 85/100 (85 %) knees. Intraoperative findings confirmed the preoperative SPECT/CT diagnosis in 32/33 knees (97 %). TKA loosening as well as progression of patellofemoral osteoarthritis (OA) was correctly diagnosed in 100 % of knees. Typical patterns of BTU for specific pathologies were identified. Loose femoral TKA components significantly correlated with increased BTU at the lateral femoral regions (p < 0.05). Loose tibial TKA components significantly correlated with increased BTU at all tibial regions (p < 0.05) and around the tibial peg (p > 0.01).
CONCLUSION: The diagnostic benefits of SPECT/CT in patients after TKA have been proven. Typical pathology-related BTU patterns were identified, which will improve reporting quality. Due to the benefits in establishing the correct diagnosis, SPECT/CT should be part of the routine diagnostic algorithm for patients with pain after TKA.

Entities:  

Keywords:  Bone; CT; Component position; Knee; Replacement; SPECT; SPECT/CT; Total knee arthroplasty; Tracer uptake

Mesh:

Year:  2015        PMID: 26044121     DOI: 10.1007/s00259-015-3095-5

Source DB:  PubMed          Journal:  Eur J Nucl Med Mol Imaging        ISSN: 1619-7070            Impact factor:   9.236


  40 in total

1.  Changes in bone density after cemented total knee arthroplasty: influence of stem design.

Authors:  J H Lonner; M Klotz; C Levitz; P A Lotke
Journal:  J Arthroplasty       Date:  2001-01       Impact factor: 4.757

2.  Rotational malalignment of the femoral component in total knee arthroplasty.

Authors:  T K Fehring
Journal:  Clin Orthop Relat Res       Date:  2000-11       Impact factor: 4.176

3.  Comparison of patellar bone strain in the natural and implanted knee during simulated deep flexion.

Authors:  Clare K Fitzpatrick; Mark A Baldwin; Azhar A Ali; Peter J Laz; Paul J Rullkoetter
Journal:  J Orthop Res       Date:  2010-09-09       Impact factor: 3.494

4.  Posterior stabilized component increased femoral bone loss after total knee replacement. 5-year follow-up of 47 knees using dual energy X-ray absorptiometry.

Authors:  Tuuli Saari; Johan Uvehammer; Lars V Carlsson; Lars Regnér; Johan Kärrholm
Journal:  Knee       Date:  2006-10-02       Impact factor: 2.199

5.  Bone mineral density and single photon emission computed tomography changes after total knee arthroplasty: a 2-year follow-up study.

Authors:  Tarja Soininvaara; Tua Nikola; Esko Vanninen; Hannu Miettinen; Heikki Kröger
Journal:  Clin Physiol Funct Imaging       Date:  2007-12-11       Impact factor: 2.273

6.  Evaluation of aseptic loosening of knee prostheses by quantitative bone scintigraphy.

Authors:  R Klett; D Steiner; S Laurich; R Bauer; J Kordelle
Journal:  Nuklearmedizin       Date:  2008       Impact factor: 1.379

7.  Quantitative scintigraphic evaluation of total knee arthroplasties: a feasibility study.

Authors:  G M Sacchetti; F Ghisellini; M Brambilla; A De Consoli; P Fornara; E Rizzo; M Rudoni; E Inglese; M Cannas
Journal:  Clin Orthop Relat Res       Date:  1996-04       Impact factor: 4.176

8.  Assessment of in vivo loading history of the patellofemoral joint: a study combining patellar position, tilt, alignment and bone SPECT/CT.

Authors:  Stephan N Schön; Faik K Afifi; Helmut Rasch; Felix Amsler; Niklaus F Friederich; Markus P Arnold; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-10-11       Impact factor: 4.342

9.  [Rotational malalignment of the components may cause chronic pain or early failure in total knee arthroplasty].

Authors:  S Hofmann; J Romero; E Roth-Schiffl; T Albrecht
Journal:  Orthopade       Date:  2003-06       Impact factor: 1.087

10.  Standardized volumetric 3D-analysis of SPECT/CT imaging in orthopaedics: overcoming the limitations of qualitative 2D analysis.

Authors:  Michael T Hirschmann; Christopher R Wagner; Helmut Rasch; Johann Henckel
Journal:  BMC Med Imaging       Date:  2012-03-29       Impact factor: 1.930

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  17 in total

1.  Intra- and postoperative assessment of femoral component rotation in total knee arthroplasty: an EKA knee expert group clinical review.

Authors:  Paweł Skowronek; Markus Arnold; Christian Starke; Agnieszka Bartyzel; Lukas B Moser; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2020-04-30       Impact factor: 4.342

2.  Increased in vivo patellofemoral loading after total knee arthroplasty in resurfaced patellae.

Authors:  Omer Slevin; Florian A Schmid; Filippo Schiapparelli; Helmut Rasch; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-11-29       Impact factor: 4.342

3.  Correlation of Uptake Patterns on Single-Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) and Treatment Response in Patients with Knee Pain.

Authors:  Geon Koh; Kyung Hoon Hwang; Haejun Lee; Seog Gyun Kim; Beom Koo Lee
Journal:  Nucl Med Mol Imaging       Date:  2015-10-26

4.  Coronal femoral TKA position significantly influences in vivo patellar loading in unresurfaced patellae after primary total knee arthroplasty.

Authors:  Omer Slevin; Florian A Schmid; Filippo-Franco Schiapparelli; Helmut Rasch; Felix Amsler; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-06-26       Impact factor: 4.342

5.  Bloodpool SPECT as part of bone SPECT/CT in painful total knee arthroplasty (TKA): validation and potential biomarker of prosthesis biomechanics.

Authors:  Jolien Verschueren; Adrien Albert; Laurens Carp; Sarah Ceyssens; Ivan Huyghe; Sigrid Stroobants; Frédéric Paycha; Gopinath Gnanasegaran; Tim Van den Wyngaert
Journal:  Eur J Nucl Med Mol Imaging       Date:  2019-01-02       Impact factor: 9.236

6.  Neutral alignment leads to higher knee society scores after total knee arthroplasty in preoperatively non-varus patients: a prospective clinical study using 3D-CT.

Authors:  Omer Slevin; Anna Hirschmann; Filippo F Schiapparelli; Felix Amsler; Rolf W Huegli; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-10-12       Impact factor: 4.342

7.  Patterns of bone tracer uptake on SPECT-CT in symptomatic and asymptomatic patients with primary total hip arthroplasty.

Authors:  Thierry Schweizer; Filippo-Franco Schiapparelli; Niccolo Rotigliano; Helmut Rasch; Felix Amsler; Michael T Hirschmann
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-09-19       Impact factor: 9.236

Review 8.  Tibial internal rotation negatively affects clinical outcomes in total knee arthroplasty: a systematic review.

Authors:  Alfredo Schiavone Panni; Francesco Ascione; Marco Rossini; Adriano Braile; Katia Corona; Michele Vasso; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-12-15       Impact factor: 4.342

9.  Symptomatic versus asymptomatic knees after bilateral total knee arthroplasty: what is the difference in SPECT/CT?

Authors:  R Awengen; H Rasch; F Amsler; M T Hirschmann
Journal:  Eur J Nucl Med Mol Imaging       Date:  2015-12-15       Impact factor: 9.236

10.  Reasons for failure in primary total knee arthroplasty - An analysis of prospectively collected registry data.

Authors:  Dominic T Mathis; Leif Lohrer; Felix Amsler; Michael T Hirschmann
Journal:  J Orthop       Date:  2020-12-31
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