Literature DB >> 26037989

Infrastructure and clinical practice for the detection and management of trauma-associated haemorrhage and coagulopathy.

A Driessen1, N Schäfer, V Albrecht, M Schenk, M Fröhlich, E K Stürmer, M Maegele.   

Abstract

PURPOSE: Early detection and management of post-traumatic haemorrhage and coagulopathy have been associated with improved outcomes, but local infrastructures, logistics and clinical strategies may differ.
METHODS: To assess local differences in infrastructure, logistics and clinical management of trauma-associated haemorrhage and coagulopathy, we have conducted a web-based survey amongst the delegates to the 15th European Congress of Trauma and Emergency Surgery (ECTES) and the 2nd World Trauma (WT) Congress held in Frankfurt, Germany, 25-27 May 2014.
RESULTS: 446/1,540 delegates completed the questionnaire yielding a response rate of 29%. The majority specified to work as consultants/senior physicians (47.3%) in general (36.1%) or trauma/orthopaedic surgery (44.5%) of level I (70%) or level II (19%) trauma centres. Clinical assessment (>80%) and standard coagulation assays (74.6%) are the most frequently used strategies for early detection and monitoring of bleeding trauma patients with coagulopathy. Only 30% of the respondents declared to use extended coagulation assays to better characterise the bleeding and coagulopathy prompted by more individualised treatment concepts. Most trauma centres (69%) have implemented local protocols based on international and national guidelines using conventional blood products, e.g. packed red blood cell concentrates (93.3%), fresh frozen plasma concentrates (93.3%) and platelet concentrates (83%), and antifibrinolytics (100%). 89% considered the continuous intake of anticoagulants including "new oral anticoagulants" and platelet inhibitors as an increasing threat to bleeding trauma patients.
CONCLUSIONS: This study confirms differences in infrastructure, logistics and clinical practice for the detection and management of trauma-haemorrhage and trauma-associated coagulopathy amongst international centres. Ongoing work will focus on geographical differences.

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Year:  2014        PMID: 26037989     DOI: 10.1007/s00068-014-0455-y

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  34 in total

1.  Early coagulopathy predicts mortality in trauma.

Authors:  Jana B A MacLeod; Mauricio Lynn; Mark G McKenney; Stephen M Cohn; Mary Murtha
Journal:  J Trauma       Date:  2003-07

2.  The causes of death in conventional land warfare: implications for combat casualty care research.

Authors:  R F Bellamy
Journal:  Mil Med       Date:  1984-02       Impact factor: 1.437

3.  Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.

Authors:  Carl J Hauser; Kenneth Boffard; Richard Dutton; Gordon R Bernard; Martin A Croce; John B Holcomb; Ari Leppaniemi; Michael Parr; Jean-Louis Vincent; Bartholomew J Tortella; Jeannett Dimsits; Bertil Bouillon
Journal:  J Trauma       Date:  2010-09

4.  Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates.

Authors:  S T Hiippala; G J Myllylä; E M Vahtera
Journal:  Anesth Analg       Date:  1995-08       Impact factor: 5.108

5.  Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival.

Authors:  Oliver L Gunter; Brigham K Au; James M Isbell; Nathan T Mowery; Pampee P Young; Bryan A Cotton
Journal:  J Trauma       Date:  2008-09

Review 6.  Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2013-04-19       Impact factor: 9.097

Review 7.  The coagulopathy of trauma: a review of mechanisms.

Authors:  John R Hess; Karim Brohi; Richard P Dutton; Carl J Hauser; John B Holcomb; Yoram Kluger; Kevin Mackway-Jones; Michael J Parr; Sandro B Rizoli; Tetsuo Yukioka; David B Hoyt; Bertil Bouillon
Journal:  J Trauma       Date:  2008-10

8.  The relationship of blood product ratio to mortality: survival benefit or survival bias?

Authors:  Christopher W Snyder; Jordan A Weinberg; Gerald McGwin; Sherry M Melton; Richard L George; Donald A Reiff; James M Cross; Jennifer Hubbard-Brown; Loring W Rue; Jeffrey D Kerby
Journal:  J Trauma       Date:  2009-02

9.  Epidemiology of trauma deaths: a reassessment.

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10.  Reappraising the concept of massive transfusion in trauma.

Authors:  Simon J Stanworth; Timothy P Morris; Christine Gaarder; J Carel Goslings; Marc Maegele; Mitchell J Cohen; Thomas C König; Ross A Davenport; Jean-Francois Pittet; Pär I Johansson; Shubha Allard; Tony Johnson; Karim Brohi
Journal:  Crit Care       Date:  2010-12-30       Impact factor: 9.097

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  4 in total

1.  Practice management of acute trauma haemorrhage and haemostatic disorders across German trauma centres.

Authors:  V Albrecht; N Schäfer; E K Stürmer; A Driessen; L Betsche; M Schenk; M Maegele
Journal:  Eur J Trauma Emerg Surg       Date:  2015-11-30       Impact factor: 3.693

2.  Diversity in clinical management and protocols for the treatment of major bleeding trauma patients across European level I Trauma Centres.

Authors:  Nadine Schäfer; Arne Driessen; Matthias Fröhlich; Ewa K Stürmer; Marc Maegele
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2015-10-01       Impact factor: 2.953

3.  Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England.

Authors:  Helen E Campbell; Elizabeth A Stokes; Danielle N Bargo; Nicola Curry; Fiona E Lecky; Antoinette Edwards; Maralyn Woodford; Frances Seeney; Simon Eaglestone; Karim Brohi; Alastair M Gray; Simon J Stanworth
Journal:  Crit Care       Date:  2015-07-06       Impact factor: 9.097

4.  Increased Geriatric Treatment Frequency Improves Mobility and Secondary Fracture Prevention in Older Adult Hip Fracture Patients-An Observational Cohort Study of 23,828 Patients from the Registry for Geriatric Trauma (ATR-DGU).

Authors:  Johannes Gleich; Evi Fleischhacker; Katherine Rascher; Thomas Friess; Christian Kammerlander; Wolfgang Böcker; Benjamin Bücking; Ulrich Liener; Michael Drey; Christine Höfer; Carl Neuerburg
Journal:  J Clin Med       Date:  2021-11-23       Impact factor: 4.241

  4 in total

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