Literature DB >> 26619853

Practice management of acute trauma haemorrhage and haemostatic disorders across German trauma centres.

V Albrecht1, N Schäfer2, E K Stürmer2, A Driessen3,2, L Betsche2, M Schenk2, M Maegele3,2.   

Abstract

PURPOSE: Early detection and management of trauma haemorrhage and coagulopathy have been associated with improved outcomes. We assessed infrastructure, logistics and management practice of trauma-associated haemorrhage and coagulopathy across German trauma centres.
METHODS: A web-based survey of 20 questions was developed using the open source survey application LimeSurvey®. It was disseminated among surgeons and anaesthetists in Germany.
RESULTS: 145 Questionnaires were returned of which 106 were completed and analysed. Two-thirds of the respondents declared they worked in level I trauma centres. Only 61 % followed a treatment algorithm. Over 90 % used standard laboratory and coagulation tests for decision-making. 56.6 % declared they additionally used extended coagulation assays (TEG/ROTEM). Packed red blood cells, fresh frozen plasma, platelet concentrates, prothrombin complex concentrates, tranexamic acid, calcium, fibrinogen and vitamin K were used by more than 85 % of the respondents for the initial treatment. In all hospitals, irrespective of care level, the first blood product was administered in less than 30 min upon patient arrival (49 % <15 min, 48.1 % <30 min). New oral anticoagulants (NOACs) were identified as an increasing problem in today`s trauma care (>95 %) and 65 % of the respondents necessitated reliable tests for early risk stratification. 57.6 % necessitated interdisciplinary training programs to improve clinical skills.
CONCLUSIONS: There is variation in the local infrastructure, logistics and management of trauma haemorrhage and coagulopathy across German trauma centres. More than one-third of the respondents declare they do not consistently follow a treatment algorithm. NOACs are considered as an increasing problem in acute trauma care.

Entities:  

Keywords:  Coagulopathy; Management; NOACs; Survey; Trauma haemorrhage; Treatment algorithm

Mesh:

Substances:

Year:  2015        PMID: 26619853     DOI: 10.1007/s00068-015-0608-7

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  30 in total

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Journal:  J Trauma       Date:  2003-07

2.  Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.

Authors:  Carl J Hauser; Kenneth Boffard; Richard Dutton; Gordon R Bernard; Martin A Croce; John B Holcomb; Ari Leppaniemi; Michael Parr; Jean-Louis Vincent; Bartholomew J Tortella; Jeannett Dimsits; Bertil Bouillon
Journal:  J Trauma       Date:  2010-09

Review 3.  Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia.

Authors:  Ewurabena Simpson; Yulia Lin; Simon Stanworth; Janet Birchall; Carolyn Doree; Chris Hyde
Journal:  Cochrane Database Syst Rev       Date:  2012-03-14

4.  Global differences in causes, management, and survival after severe trauma: the recombinant activated factor VII phase 3 trauma trial.

Authors:  Michael C Christensen; Michael Parr; Bartholomew J Tortella; Johan Malmgren; Stephen Morris; Todd Rice; John B Holcomb
Journal:  J Trauma       Date:  2010-08

5.  Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival.

Authors:  Oliver L Gunter; Brigham K Au; James M Isbell; Nathan T Mowery; Pampee P Young; Bryan A Cotton
Journal:  J Trauma       Date:  2008-09

Review 6.  Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2013-04-19       Impact factor: 9.097

Review 7.  Exsanguination in trauma: A review of diagnostics and treatment options.

Authors:  L M G Geeraedts; H A H Kaasjager; A B van Vugt; J P M Frölke
Journal:  Injury       Date:  2009-01-08       Impact factor: 2.586

Review 8.  The coagulopathy of trauma: a review of mechanisms.

Authors:  John R Hess; Karim Brohi; Richard P Dutton; Carl J Hauser; John B Holcomb; Yoram Kluger; Kevin Mackway-Jones; Michael J Parr; Sandro B Rizoli; Tetsuo Yukioka; David B Hoyt; Bertil Bouillon
Journal:  J Trauma       Date:  2008-10

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Authors:  A Sauaia; F A Moore; E E Moore; K S Moser; R Brennan; R A Read; P T Pons
Journal:  J Trauma       Date:  1995-02

10.  Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial.

Authors:  Ian Roberts; Pablo Perel; David Prieto-Merino; Haleema Shakur; Tim Coats; Beverley J Hunt; Fiona Lecky; Karim Brohi; Keith Willett
Journal:  BMJ       Date:  2012-09-11
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  3 in total

Review 1.  [Approaches to pre-hospital bleeding management : Current overview on civilian emergency medicine].

Authors:  H Lier; M Bernhard; J Knapp; C Buschmann; I Bretschneider; B Hossfeld
Journal:  Anaesthesist       Date:  2017-11       Impact factor: 1.041

2.  The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Jacques Duranteau; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Marc Maegele; Giuseppe Nardi; Louis Riddez; Charles-Marc Samama; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2019-03-27       Impact factor: 9.097

3.  The impact of prehospital tranexamic acid on mortality and transfusion requirements: match-pair analysis from the nationwide German TraumaRegister DGU®.

Authors:  Sebastian Imach; Arasch Wafaisade; Rolf Lefering; Andreas Böhmer; Mark Schieren; Victor Suárez; Matthias Fröhlich
Journal:  Crit Care       Date:  2021-08-04       Impact factor: 9.097

  3 in total

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