| Literature DB >> 26037603 |
Mark L Wahlqvist1, Stephen A Krawetz2, Nico S Rizzo3,4, Maria Gloria Dominguez-Bello5, Linda M Szymanski6, Shari Barkin7, Ann Yatkine7, Robert A Waterland8, Julie A Mennella9, Mina Desai10, Michael G Ross10, Nancy F Krebs11, Bridget E Young11, Jane Wardle12, Christiane D Wrann13, John G Kral14.
Abstract
The double burden of under- and overnutrition profoundly affects human health globally. According to the World Health Organization, obesity and diabetes rates have almost doubled worldwide since 1980, and, in 2011, more than 40 million children under 5 years of age were overweight. Ecologic factors, parental genetics and fitness, and the intrauterine environment significantly influence the likelihood of offspring developing the dysmetabolic diathesis of obesity. This report examines the effects of these factors, including preconception, intrauterine and postnatal energy balance affecting programming of transgenerational transmission, and development of chronic diseases later in life-in particular, diabesity and its comorbidities.Entities:
Keywords: breast feeding; diabesity; econutritional; epigenetics; exercise; microbiome; nutrition; obesity; taste preferences
Mesh：
Year: 2015 PMID： 26037603 PMCID： PMC4522218 DOI： 10.1111/nyas.12778
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691