| Literature DB >> 26035733 |
Larisa K Shubina1, Tatyana N Makarieva1, Dmitry V Yashunsky2, Nikolay E Nifantiev2, Vladimir A Denisenko1, Pavel S Dmitrenok1, Sergey A Dyshlovoy1, Sergey N Fedorov1, Vladimir B Krasokhin1, Seung Hun Jeong3, Jin Han3, Valentin A Stonik1.
Abstract
Neopetrosides A (1) and B (2), new naturally occurring ribosides of nicotinic acid with extremely rare α-N-glycoside linkages and residues of p-hydroxybenzoic and pyrrole-2-carboxylic acids attached to C-5', were isolated from a marine Neopetrosia sp. sponge. Structures 1 and 2 were determined by NMR and MS methods and confirmed by the synthesis of 1 and its β-riboside analogue (3). Neopetroside A (1) upregulates mitochondrial functions in cardiomyocytes.Entities:
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Year: 2015 PMID： 26035733 DOI： 10.1021/acs.jnatprod.5b00256
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050