Literature DB >> 26035189

Longitudinal trajectories of ADHD symptomatology in offspring of parents with bipolar disorder and community controls.

Jae-Won Kim1, Haifeng Yu, Neal D Ryan, David A Axelson, Benjamin I Goldstein, Tina R Goldstein, Rasim S Diler, Kelly Monk, Mary Beth Hickey, Dara J Sakolsky, John A Merranko, Boris Birmaher.   

Abstract

OBJECTIVE: To compare the psychopathology and longitudinal course of attention-deficit/hyperactivity disorder (ADHD) symptomatology and global functioning between the offspring with ADHD of parents with bipolar disorder and the offspring with ADHD of community control parents.
METHOD: One hundred twenty-two offspring with ADHD of parents with bipolar disorder and 48 offspring with ADHD of control parents from the Pittsburgh Bipolar Offspring Study (BIOS) were included. DSM-IV lifetime psychiatric disorders were ascertained through the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL). The outcome measures of ADHD symptoms were ascertained at intake and every other year for a period of 6 years using the ADHD section of the K-SADS-PL and the Disruptive Behavior Disorder rating scale (DBD). Global functioning was assessed using the Children's Global Assessment Scale (CGAS).
RESULTS: The offspring with ADHD of parents with bipolar disorder showed higher lifetime prevalence of mood and anxiety disorders relative to the offspring with ADHD of control parents (P values ≤ .03). For both groups of offspring with ADHD, the hyperactivity, impulsivity, and total K-SADS-PL ADHD scores decreased over time (P values < .001) without differences between the 2 groups. There were no between- or within-group differences in the inattention scores over time. The DBD ADHD scores decreased with age in both groups (P values < .002) without differences between the 2 groups. For both groups of offspring with ADHD, the global functioning did not improve over time.
CONCLUSIONS: Offspring with ADHD of parents with bipolar disorder have more psychopathology relative to offspring with ADHD of control parents. However, there were no differences in the developmental courses of ADHD symptomatology between these 2 groups of ADHD youth. © Copyright 2015 Physicians Postgraduate Press, Inc.

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Year:  2015        PMID: 26035189      PMCID: PMC5445724          DOI: 10.4088/JCP.14m09095

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  29 in total

1.  Lifetime co-morbidity of DSM-IV disorders in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A).

Authors:  R C Kessler; S Avenevoli; K A McLaughlin; J Greif Green; M D Lakoma; M Petukhova; D S Pine; N A Sampson; A M Zaslavsky; K Ries Merikangas
Journal:  Psychol Med       Date:  2012-01-25       Impact factor: 7.723

Review 2.  The nature of the association between childhood ADHD and the development of bipolar disorder: a review of prospective high-risk studies.

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Journal:  Am J Psychiatry       Date:  2012-12       Impact factor: 18.112

Review 3.  Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specified.

Authors:  David A Axelson; Boris Birmaher; Michael A Strober; Benjamin I Goldstein; Wonho Ha; Mary Kay Gill; Tina R Goldstein; Shirley Yen; Heather Hower; Jeffrey I Hunt; Fangzi Liao; Satish Iyengar; Daniel Dickstein; Eunice Kim; Neal D Ryan; Erica Frankel; Martin B Keller
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2011-09-08       Impact factor: 8.829

Review 4.  Co-occurrence of bipolar and attention-deficit hyperactivity disorders in children.

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Journal:  Bipolar Disord       Date:  2006-12       Impact factor: 6.744

5.  Clinical, demographic, and familial correlates of bipolar spectrum disorders among offspring of parents with bipolar disorder.

Authors:  Benjamin I Goldstein; Wael Shamseddeen; David A Axelson; Cathy Kalas; Kelly Monk; David A Brent; David J Kupfer; Boris Birmaher
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2010-04       Impact factor: 8.829

6.  Psychiatric disorders in preschool offspring of parents with bipolar disorder: the Pittsburgh Bipolar Offspring Study (BIOS).

Authors:  Boris Birmaher; David Axelson; Benjamin Goldstein; Kelly Monk; Catherine Kalas; Mihaela Obreja; Mary Beth Hickey; Satish Iyengar; David Brent; Wael Shamseddeen; Rasim Diler; David Kupfer
Journal:  Am J Psychiatry       Date:  2010-01-15       Impact factor: 18.112

7.  Examining the comorbidity between attention deficit hyperactivity disorder and bipolar I disorder: a meta-analysis of family genetic studies.

Authors:  Stephen V Faraone; Joseph Biederman; Janet Wozniak
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9.  The MTA at 8 years: prospective follow-up of children treated for combined-type ADHD in a multisite study.

Authors:  Brooke S G Molina; Stephen P Hinshaw; James M Swanson; L Eugene Arnold; Benedetto Vitiello; Peter S Jensen; Jeffery N Epstein; Betsy Hoza; Lily Hechtman; Howard B Abikoff; Glen R Elliott; Laurence L Greenhill; Jeffrey H Newcorn; Karen C Wells; Timothy Wigal; Robert D Gibbons; Kwan Hur; Patricia R Houck
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2009-05       Impact factor: 8.829

Review 10.  Age-dependent expression of attention-deficit/hyperactivity disorder symptoms.

Authors:  Eric Mick; Stephen V Faraone; Joseph Biederman
Journal:  Psychiatr Clin North Am       Date:  2004-06
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Journal:  Eur Child Adolesc Psychiatry       Date:  2017-03-10       Impact factor: 4.785

2.  Predictive value of dysregulation profile trajectories in childhood for symptoms of ADHD, anxiety and depression in late adolescence.

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3.  Timely Research in Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder.

Authors:  Philip Shaw; Hilary P Blumberg
Journal:  Biol Psychiatry       Date:  2017-11-01       Impact factor: 13.382

4.  Longitudinal Associations Between Sleep Patterns and Psychiatric Symptom Severity in High-Risk and Community Comparison Youth.

Authors:  Adriane M Soehner; Michele A Bertocci; Jessica C Levenson; Tina R Goldstein; Brian Rooks; John Merranko; Danella Hafeman; Rasim Diler; David Axelson; Benjamin I Goldstein; Mary Beth Hickey; Kelly Monk; Mary L Phillips; Boris Birmaher
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2019-03-06       Impact factor: 8.829

5.  Medication exposure and predictors of first mood episode in offspring of parents with bipolar disorder: a prospective study.

Authors:  Fabiano G Nery; Anna R Wilson; Marguerite R Schneider; Jeffrey R Strawn; Luis R Patino; Robert K McNamara; Caleb M Adler; Stephen M Strakowski; Melissa P DelBello
Journal:  Braz J Psychiatry       Date:  2020 Sep-Oct       Impact factor: 2.697

6.  ADHD and Academic Success in University Students: The Important Role of Impaired Attention.

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  6 in total

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