Literature DB >> 26031336

Pluripotency and Epigenetic Factors in Mouse Embryonic Stem Cell Fate Regulation.

Lluis Morey1, Alexandra Santanach1, Luciano Di Croce2.   

Abstract

Embryonic stem cells (ESCs) are characterized by their ability to self-renew and to differentiate into all cell types of a given organism. Understanding the molecular mechanisms that govern the ESC state is of great interest not only for basic research-for instance, ESCs represent a perfect system to study cellular differentiation in vitro-but also for their potential implications in human health, as these mechanisms are likewise involved in cancer progression and could be exploited in regenerative medicine. In this minireview, we focus on the latest insights into the molecular mechanisms mediated by the pluripotency factors as well as their roles during differentiation. We also discuss recent advances in understanding the function of the epigenetic regulators, Polycomb and MLL complexes, in ESC biology.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26031336      PMCID： PMC4508320          DOI： 10.1128/MCB.00266-15

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  133 in total

1.  Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.

Authors:  Stephen Frankenberg; François Gerbe; Sylvain Bessonnard; Corinne Belville; Pierre Pouchin; Olivier Bardot; Claire Chazaud
Journal:  Dev Cell       Date:  2011-12-13       Impact factor: 12.270

2.  Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development.

Authors:  E Arman; R Haffner-Krausz; Y Chen; J K Heath; P Lonai
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-28       Impact factor: 11.205

3.  Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.

Authors:  Katrin Arnold; Abby Sarkar; Mary Anna Yram; Jose M Polo; Rod Bronson; Sumitra Sengupta; Marco Seandel; Niels Geijsen; Konrad Hochedlinger
Journal:  Cell Stem Cell       Date:  2011-10-04       Impact factor: 24.633

4.  CBX7 is a tumor suppressor in mice and humans.

Authors:  Floriana Forzati; Antonella Federico; Pierlorenzo Pallante; Adele Abbate; Francesco Esposito; Umberto Malapelle; Romina Sepe; Giuseppe Palma; Giancarlo Troncone; Marzia Scarfò; Claudio Arra; Monica Fedele; Alfredo Fusco
Journal:  J Clin Invest       Date:  2012-01-03       Impact factor: 14.808

5.  Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.

Authors:  H Yuan; N Corbi; C Basilico; L Dailey
Journal:  Genes Dev       Date:  1995-11-01       Impact factor: 11.361

6.  Requirement of FGF-4 for postimplantation mouse development.

Authors:  B Feldman; W Poueymirou; V E Papaioannou; T M DeChiara; M Goldfarb
Journal:  Science       Date:  1995-01-13       Impact factor: 47.728

7.  Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor.

Authors:  C L Stewart; P Kaspar; L J Brunet; H Bhatt; I Gadi; F Köntgen; S J Abbondanzo
Journal:  Nature       Date:  1992-09-03       Impact factor: 49.962

8.  Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

Authors:  Lluis Morey; Gloria Pascual; Luca Cozzuto; Guglielmo Roma; Anton Wutz; Salvador Aznar Benitah; Luciano Di Croce
Journal:  Cell Stem Cell       Date:  2012-01-06       Impact factor: 24.633

9.  MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.

Authors:  Ana O'Loghlen; Ana M Muñoz-Cabello; Alexandre Gaspar-Maia; Hsan-Au Wu; Ana Banito; Natalia Kunowska; Tomas Racek; Helen N Pemberton; Patrizia Beolchi; Fabrice Lavial; Osamu Masui; Michiel Vermeulen; Thomas Carroll; Johannes Graumann; Edith Heard; Niall Dillon; Veronique Azuara; Ambrosius P Snijders; Gordon Peters; Emily Bernstein; Jesus Gil
Journal:  Cell Stem Cell       Date:  2012-01-06       Impact factor: 24.633

10.  The eed mutation disrupts anterior mesoderm production in mice.

Authors:  C Faust; A Schumacher; B Holdener; T Magnuson
Journal:  Development       Date:  1995-02       Impact factor: 6.868
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  38 in total

1.  Making gametes from pluripotent stem cells: embryonic stem cells or very small embryonic-like stem cells?

Authors:  Deepa Bhartiya; Sandhya Anand; Hiren Patel
Journal:  Stem Cell Investig       Date:  2016-10-18

2.  Polycomb meets mediator to balance pluripotency and differentiation.

Authors:  Lluis Morey
Journal:  Cell Cycle       Date:  2016-05-06       Impact factor: 4.534

Review 3.  Chromatin and Epigenetics at the Forefront: Finding Clues among Peaks.

Authors:  Sergi Aranda; Yang Shi; Luciano Di Croce
Journal:  Mol Cell Biol       Date:  2016-09-12       Impact factor: 4.272

4.  ZSCAN4+ mouse embryonic stem cells have an oxidative and flexible metabolic profile.

Authors:  Annaelena Troiano; Consiglia Pacelli; Claudia Piccoli; Geppino Falco; Vitalba Ruggieri; Rosella Scrima; Martina Addeo; Francesca Agriesti; Valeria Lucci; Gina Cavaliere; Maria Pina Mollica; Marianna Caterino; Margherita Ruoppolo; Simona Paladino; Daniela Sarnataro; Feliciano Visconte; Francesco Tucci; Piervito Lopriore; Viola Calabrò; Nazzareno Capitanio
Journal:  EMBO Rep       Date:  2020-05-18       Impact factor: 8.807

5.  Arid4b is critical for mouse embryonic stem cell differentiation towards mesoderm and endoderm, linking epigenetics to pluripotency exit.

Authors:  Nihal Terzi Cizmecioglu; Jialiang Huang; Ezgi G Keskin; Xiaofeng Wang; Idil Esen; Fei Chen; Stuart H Orkin
Journal:  J Biol Chem       Date:  2020-10-15       Impact factor: 5.157

6.  TGMI: an efficient algorithm for identifying pathway regulators through evaluation of triple-gene mutual interaction.

Authors:  Chathura Gunasekara; Kui Zhang; Wenping Deng; Laura Brown; Hairong Wei
Journal:  Nucleic Acids Res       Date:  2018-06-20       Impact factor: 16.971

7.  Single-cell gene expression of the bovine blastocyst.

Authors:  Verónica M Negrón-Pérez; Yanping Zhang; Peter J Hansen
Journal:  Reproduction       Date:  2017-08-16       Impact factor: 3.906

8.  The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes.

Authors:  Haixin Zhao; Zhijun Han; Xinyuan Liu; Junjie Gu; Fan Tang; Gang Wei; Ying Jin
Journal:  J Biol Chem       Date:  2017-03-15       Impact factor: 5.157

Review 9.  Chromatin regulation and dynamics in stem cells.

Authors:  David C Klein; Sarah J Hainer
Journal:  Curr Top Dev Biol       Date:  2019-12-30       Impact factor: 4.897

10.  Polycomb group RING finger proteins 3/5 activate transcription via an interaction with the pluripotency factor Tex10 in embryonic stem cells.

Authors:  Wukui Zhao; Yikai Huang; Jingzi Zhang; Mengjie Liu; Haijing Ji; Congcong Wang; Ning Cao; Chaojun Li; Yin Xia; Qing Jiang; Jinzhong Qin
Journal:  J Biol Chem       Date:  2017-10-20       Impact factor: 5.157
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