Literature DB >> 26030521

Crisis Awaiting Heart Transplantation: Sinking the Lifeboat.

Lynne Warner Stevenson1.   

Abstract

The number of heart transplants performed in the United States was 2177 in 1994 and 2166 in 2014. However, the number of transplant centers has increased, and the criteria for transplants have broadened to include patients 65 years or older, those with a body mass index greater than 30, and more comorbid conditions, such as diabetes mellitus and a history of smoking. As the transplant waiting list has become longer and waiting times have increased, the major route to heart transplants has become deterioration to the most urgent priority status, which accounts for 10% of patients on the waiting list but two-thirds of transplants. Many heart transplant candidates develop life-threatening complications of a ventricular assist device implanted to avert death while waiting. Some affluent patients, however, can afford to temporarily relocate and obtain a transplant in regions where the waiting times are shorter without prior surgery to implant a ventricular assist device. The ethics of allocating hearts for transplant have always recalled the classic lifeboat dilemma of how many people can be allowed to board an already overcrowded lifeboat without sinking the ship and everyone on board. As transplant physicians, we advocate with the best intentions on behalf of our own patients rather than denying transplants to those less likely to benefit. In recognizing our responsibilities as stewards of scarce donor hearts, we should reduce new listings for heart transplants, thus restoring balance to the waiting list and keeping the lifeboat afloat.

Entities:  

Mesh:

Year:  2015        PMID: 26030521     DOI: 10.1001/jamainternmed.2015.2203

Source DB:  PubMed          Journal:  JAMA Intern Med        ISSN: 2168-6106            Impact factor:   21.873


  11 in total

Review 1.  Integrating palliative care into routine care of patients with heart failure: models for clinical collaboration.

Authors:  Warren H Lewin; Kristen G Schaefer
Journal:  Heart Fail Rev       Date:  2017-09       Impact factor: 4.214

2.  Association Between Heart Transplantation and Subsequent Risk of Stroke Among Patients With Heart Failure.

Authors:  Alexander E Merkler; Monica L Chen; Neal S Parikh; Santosh B Murthy; Shadi Yaghi; Parag Goyal; Peter M Okin; Maria G Karas; Babak B Navi; Costantino Iadecola; Hooman Kamel
Journal:  Stroke       Date:  2019-03       Impact factor: 7.914

3.  High early event rates in patients with questionable eligibility for advanced heart failure therapies: Results from the Medical Arm of Mechanically Assisted Circulatory Support (Medamacs) Registry.

Authors:  Amrut V Ambardekar; Rhondalyn C Forde-McLean; Michelle M Kittleson; Garrick C Stewart; Maryse Palardy; Jennifer T Thibodeau; Adam D DeVore; Maria M Mountis; Linda Cadaret; Jeffrey J Teuteberg; Salpy V Pamboukian; Ryan S Cantor; JoAnn Lindenfeld
Journal:  J Heart Lung Transplant       Date:  2016-01-18       Impact factor: 10.247

4.  Strategies of Wait-listing for Heart Transplant vs Durable Mechanical Circulatory Support Alone for Patients With Advanced Heart Failure.

Authors:  Anuradha Lala; John C Rowland; Bart S Ferket; Annetine C Gelijns; Emilia Bagiella; Sean P Pinney; Alan J Moskowitz; Marissa A Miller; Francis D Pagani; Donna M Mancini
Journal:  JAMA Cardiol       Date:  2020-06-01       Impact factor: 14.676

Review 5.  Matching the Market for Heart Transplantation.

Authors:  Eileen M Hsich
Journal:  Circ Heart Fail       Date:  2016-04       Impact factor: 8.790

6.  Optimal and Equitable Allocation of Donor Hearts: Which Principles Are We Translating Into Practices?

Authors:  Maria Frigerio
Journal:  Transplant Direct       Date:  2017-07-18

Review 7.  New role of ventricular assist devices as bridge to transplantation: European perspective.

Authors:  David C Reineke; Paul J Mohacsi
Journal:  Curr Opin Organ Transplant       Date:  2017-06       Impact factor: 2.640

8.  Amiodarone Use Prior to Cardiac Transplant Impacts Early Post-Transplant Survival.

Authors:  Salman S Allana; Furqan A Rajput; Jason W Smith; Lucian Lozonschi; Jinn-Ing Liou; Maryl Johnson; Takushi Kohmoto; Ravi Dhingra
Journal:  Cardiovasc Drugs Ther       Date:  2020-10-19       Impact factor: 3.727

9.  The inodilator levosimendan in repetitive doses in the treatment of advanced heart failure.

Authors:  Juan F Delgado; Fabrizio Oliva; Alexander Reinecke
Journal:  Eur Heart J Suppl       Date:  2017-03-08       Impact factor: 1.803

10.  Efficient and Fair Heart Allocation Policies for Transplantation.

Authors:  Farhad Hasankhani; Amin Khademi
Journal:  MDM Policy Pract       Date:  2017-05-25
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